A new triazolothiadiazine derivative inhibits stemness and induces cell death in HCC by oxidative stress dependent JNK pathway activation. [PDF]
Kahraman DC +5 more
europepmc +1 more source
Review on Synthetic Strategies for 1,3,4-Thiadiazines and its Biological Activity
Heterocycles containing nitrogen and sulfur, known as thiazine, play a vital role in pharmaceutical chemistry and agriculture chemistry. The thiadiazines compound contains one sulfur and two nitrogen atoms at varied positions in six-membered rings. Thiadiazines possess an N-C-S linkage that is believed to be very useful in medicinal and pharmaceutical ...
openaire +1 more source
本发明涉及一种制备1,3,4-三取代吡咯衍生物的方法,具体地说是由简单1,6二炔和胺通过环合异构化制备1,3,4-三取代吡咯衍生物的新方法。以商业廉价易得的起始原料出发,使用过渡金属作为氧化剂,经过一锅两步的方法得到1,3,4 ...
崇庆雷, 吴凡, 万伯顺
core
New quinazoline-[1,2,4]triazolo[3,4-<i>b</i>][1,3,4]thiadiazines as inhibitors of EGFR: synthesis, anti-breast cancer evaluation and <i>in silico</i> studies. [PDF]
Bandgar MD +5 more
europepmc +1 more source
Triazolothiadiazoles and Triazolothiadiazines as New and Potent Urease Inhibitors: Insights from In Vitro Assay, Kinetics Data, and In Silico Assessment. [PDF]
Uddin J +8 more
europepmc +1 more source
A Comprehensive Review on Chemical Synthesis and Chemotherapeutic Potential of 3-Heteroaryl Fluoroquinolone Hybrids. [PDF]
Hryhoriv H +4 more
europepmc +1 more source
Discovery of ( ±)-3-(1H-pyrazol-1-yl)-6,7-dihydro-5H-[1,2,4]triazolo[3,4-b][1,3,4] thiadiazine derivatives with promising in vitro anticoronavirus and antitumoral activity. [PDF]
Jilloju PC +6 more
europepmc +1 more source
Synthetic Strategies of Fused Triazole Frameworks: A Comprehensive Review. [PDF]
Tamminana R, Mohammed A.
europepmc +1 more source

