Results 1 to 10 of about 806 (175)
Immunomodulatory Action of Substituted 1,3,4-Thiadiazines on the Course of Myocardial Infarction [PDF]
Molecules, 2018 This review focuses on the biological action of the compounds from the group of substituted 1,3,4-thiadiazines on stress response and myocardial infarction.
Oleg N Chupakhin +2 more
exaly +5 more sources
Molecules, 2014 A series of newly disubstituted (compounds 4a,b) and trisubstituted 1,3,4-thiadiazines 5a–l with various substituents was prepared utilizing different thiosemicarbazides and 3-α-bromoacetylcoumarins as starting compounds.
Valentina Pavić +2 more
exaly +4 more sources
Chemometric and QSAR analysis of some thiadiazines as potential antifungal agents [PDF]
Acta Periodica Technologica, 2017 Quantitative structure-activity relationship (QSAR) analysis has been performed in order to predict the antifungal activity of dihydroindeno and indeno thiadiazines against toxigenic fungus Aspergillus flavus.
Karadžić Milica Ž. +3 more
doaj +3 more sources
Green Chemistry Letters and Reviews, 2021 In this article, we applied ultrasonic irradiation as an ecofriendly, green, efficient approach for the synthesis of a new 1,3-thiazoles and 1,3,4-thiadiazines under solvent-free conditions.
Anhar Abdel-Aziem
exaly +2 more sources
Heteropolyacides as green and reusable catalysts for the synthesis of [3,4-b][1,3,4] thiadiazines [PDF]
Bulletin of the Chemical Society of Ethiopia, 2014 Synthesis of [3,4-b][1,3,4]thiadiazines from the condensation of 4-amino-6-methyl-3-thioxo-1,2,4-triazine-5(2H)-one (AMTTO) or 4-amino-1,4-dihydro-5-methyle-1,2,4-triazole-5-thione (AMTT) with phenacyl bromide in the presence of a catalytic amount of ...
F. Hakimi +3 more
doaj +2 more sources
Bangladesh Journal of Pharmacology, 2015 This study was aimed to evaluate anticancer potential of newer synthesize 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines and its derivatives. All newly furnished scaffolds were subjected to screening for their in vitro anticancer potential against DU-145 and ...
Mao-Chuan Fan +3 more
doaj +2 more sources
Hetero-Diels-Alder Reactions of In Situ-Generated Azoalkenes with Thioketones; Experimental and Theoretical Studies [PDF]
Molecules, 2021 The hetero-Diels-Alder reactions of in situ-generated azoalkenes with thioketones were shown to offer a straightforward method for an efficient and regioselective synthesis of scarcely known N-substituted 1,3,4-thiadiazine derivatives.
Grzegorz Mlostoń +7 more
doaj +2 more sources
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2021 The problem of finding effective low-toxic anticancer agents is one of the most important in modern medicine and pharmacy. Despite a large selection of anticancer drugs and a variety of mechanisms of their action, the effectiveness of existing drugs ...
I. I. Myrko +4 more
doaj +1 more source
Thiadiazines, <em>N</em>,<em>N</em>-Heterocycles of Biological Relevance
Molecules, 2012 The 3,5-disubstituted tetrahydro-2<em>H</em>-1,3,5-thiadiazine-2-thione scaffold has found many applications in recent years. This review is aimed at highlighting the most important aspects of these compounds: Synthesis, spectroscopic ...
Hortensia Rodríguez +2 more
doaj +1 more source
Pharmaceuticals, 2016 Substituted thiadiazines exert a reliable therapeutic effect in treating stress, and a schematic description of their ability to influence all aspects of a stress response has been depicted. This study was conducted to pharmacologically evaluate compound
Alexey P. Sarapultsev +4 more
doaj +1 more source