Results 31 to 40 of about 806 (175)

Synthesis and Structure of Novel 1λ⁴,2,6-Thiadiazines

, 2016
S,S-Disubstituted sulfodiimines 9 are known to be versatile building blocks for the synthesis of various sulfur−nitrogen-containing heterocycles. Addition−condensation reactions of 9 with three different activated carbonylsubstrates 14−16 lead to several
Manfred Haake (3034236), Wibke E. Diederich (1585390)   +1 more
core   +1 more source

Synthesis and Biological Activity of Some Novel Derivatives of 4-Amino-3-(D-galactopentitol-1-yl)-5-mercapto-1,2,4-triazole

Molecules, 2007
To discover new 1,2,4-triazole derivatives which may possess significant biological activities, we synthesized a series of novel 6-aryl-3-(D-galactopentitol-1-yl)- 7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines and 4-(arylmethylidene)amino-5-(D ...
Jiang-Hai Zhu, Xin-Xiang Lei, An-jiang Zhang, Li-xue Zhang, Jian-yu Jin   +4 more
doaj   +1 more source

Impact of Tetrahydropyrido[2,1-b][1,3,5]thiadiazines on L-DOPA Effects in the Tail Suspension Test

Кубанский научный медицинский вестник, 2020
Aim. Evaluation of the impact of tetrahydropyrido[2,1-b][1,3,5]thiadiazine derivatives on L-DOPA effects in the tail suspension test.Materials and methods.
E. Yu. Bibik, I. A. Nekrasa, A. V. Demenko, K. A. Frolov, V. V. Dotsenko, S. G. Krivokolysko, A. S. Startseva   +6 more
doaj   +1 more source

3-Chloro-5-(4-dodecylthiophen-2-yl)-4H-1,2,6-thiadiazin-4-one

Molbank, 2012
3-Chloro-5-trifluoromethanesulfonate-4H-1,2,6-thiadiazin-4-one 3 reacts with (4-dodecylthiophen-2-yl)trimethylstannane 5 (1 equiv.) in the presence of Pd(Ph3P)2Cl2 (5 mol%) in benzene at ca.
Panayiotis A. Koutentis, Heraklidia A. Ioannidou   +1 more
doaj   +1 more source

Effects of a compound from the group of substituted thiadiazines with hypothermia inducing properties on brain metabolism in rats, a study in vivo and in vitro. [PDF]

PLoS ONE, 2017
The aim of the present study was to examine how administration of a compound of 1,3,4- thiadiazine class 2-morpholino-5-phenyl-6H-1,3,4-thiadiazine, hydrobromide (L-17) with hypothermia inducing properties affects the brain metabolism.
O B Shevelev, N B Illarionova, D V Petrovski, A P Sarapultsev, O N Chupakhin, M P Moshkin   +5 more
doaj   +1 more source

Design, Synthesis, and Antimicrobial Evaluation of Novel Pyrazoles and Pyrazolyl 1,3,4-Thiadiazine Derivatives

Molecules, 2018
A novel series of pyrazolyl 1,3,4-thiadiazines 5a–c, 8a–c, 12, 15a–c, 17a–c, and 20 was prepared from the reaction of pyrazole-1-carbothiohydrazide 1a,b with 2-oxo-N′-arylpropanehydrazonoyl chloride, 2-chloro-2-(2 ...
Ibrahim Ali M. Radini
doaj   +1 more source

Substituted 2-amino-1,3,4-thiadiazines: a novel solid-phase approach

, 2002
A novel and facile strategy for synthesis of substituted 2-amino-1,3,4-thiadiazines on solid support is described. Resin bound isothiocyanate prepared from an immobilised primary amine and di-(2-pyridyl)thionocarbonate was reacted with hydrazine hydrate ...
Jones, Raymond C. F., Kilburn, John Paul, Lau, Jesper   +2 more
core   +1 more source

An Improved Synthesis of 4-Chlorocoumarin-3-sulfonyl Chloride and Its Reactions with Different Bidentate Nucleophiles to Give Pyrido[1',2':2,3]- and Thiazino[3',2':2,3]-1,2,4-Thiadiazino[6,5-c]Benzopyran-6-one 7,7-Dioxides

Molecules, 2007
An improved synthetic method affording 4-chlorocoumarin-3-sulfonyl chloride (4) in very good yield (ca. 85 %) is reported. This compound was reacted with various bidentate nucleophiles such as 2-aminopyridines and 2-aminothiazoles in order to obtain ...
Emil Popovski, Gerald Draeger, Bozhana Mikhova, Evamarie Hey-Hawkins, Ahmed Jashari   +4 more
doaj   +1 more source

The Photochemical Mediated Ring Contraction of 4H‑1,2,6-Thiadiazines To Afford 1,2,5-Thiadiazol-3(2H)‑one 1‑Oxides

, 2023
1,2,6-Thiadiazines treated with visible light and 3O2 under ambient conditions are converted into difficult-to-access 1,2,5-thiadiazole 1-oxides (35 examples, yields of 39–100%).
Emmanouil Broumidis, Christopher G. Thomson, Christopher G. Thomson (16963710), Panayiotis A. Koutentis, Kenneth G. McKendrick (1271511), Janet E. Lovett (2045767), Georgina M. Rosair, Andreas S. Kalogirou (10525348), Janet E. Lovett, Kenneth G. McKendrick, Georgina M. Rosair (628281), Lia Sotorríos, Martin J. Paterson (1235301), Martin J. Paterson, Lia Sotorríos (8114585), Filipe Vilela (1266402), Brendan Gallagher, Stuart A. Macgregor, Stuart A. Macgregor (1350846), Gareth O. Lloyd, Brendan Gallagher (16404786), Panayiotis A. Koutentis (1278807), Emmanouil Broumidis (16963707), Filipe Vilela, Andreas S. Kalogirou, Gareth O. Lloyd (1235277)   +25 more
core   +1 more source

The Mannich Reaction of the S,N-Binucleophilic Species Derived from Meldrum’s Acid with HCHO and Primary Amines

Chemistry Proceedings
We investigated the reactivity of a new sulfur-containing compound derived from Meldrum’s acid and phenyl isothiocyanate, triethylammonium 1-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)(phenylamino)methanethiolate.
Anastasiya Yu. Skachkova, Alena A. Russkikh, Victor V. Dotsenko   +2 more
doaj   +1 more source