Results 121 to 130 of about 27,886 (261)

Inverse electron-demand 1,3-dipolar cycloaddition of nitrile oxide with common nitriles leading to 3-functionalized 1,2,4-oxadiazoles [PDF]

, 2011
A carbamoyl-substituted nitrile oxide was generated upon treatment of easily available 2-methyl-4-nitro-3-isoxazolin-5(2H)-one with THF (not dried); the reaction proceeded efficiently even in the absence of any special reagents and reaction conditions ...
1020, 1021, 1022, 1023, 1024, 1025, 1026, 1027, Ariga, Masahiro, Hirao, Shotaro, Ise, Yumiko, Kobiro, Kazuya, Nishiwaki, Nagatoshi, Okajima, Yoshikazu, Saigo, Kazuhiko, Sawayama, Jun   +15 more
core   +1 more source

Electrocyclic Ring‐Opening of 1,2,4‐Oxadiazole[4,5‐a]piridinium Chloride: a New Route to 1,2,4‐Oxadiazole Dienamino Compounds

ChemistryOpen, 2019
1,2,4‐Oxadiazole[4,5‐a]piridinium chloride adds nucleophiles to undergo electrocyclic ring opening affording 1,2,4‐oxadiazole dienamino derivatives. These pyridinium salts represent a special class of Zincke salts that are prone to rearrange when treated
Dr. Stefano Carella, Dr. Misal Giuseppe Memeo, Prof. Paolo Quadrelli   +2 more
doaj   +1 more source

Development and pharmacological characterization of novel multi‐ calcitonin gene‐related peptide and pituitary adenylate cyclase‐activating peptide receptor antagonists

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study aimed to provide proof‐of‐concept that multi‐receptor antagonist peptides can be generated by covalently linking independent antagonist peptides that block calcitonin gene‐related peptide (CGRP8‐37) or pituitary adenylate cyclase‐activating peptide (PACAP)/vasoactive intestinal peptide (VIP) (PACAP6‐38) activity ...
Zoe Tasma, Andrew Siow, Paul W. R. Harris, Margaret A. Brimble, Debbie L. Hay, Christopher S. Walker   +5 more
wiley   +1 more source

1,3-dipolar cycloadditions of aldehydes or Imines with carbonyl ylides generated from epoxides: Classical heating and microwave irradiation

, 2007
International audienceCycloadditions of aldehydes with carbonyl ylides to give dioxolanes have been carried out without solvent under microwave irradiation. The reactions proceeded in similar yields and stereoselectivities, but in shorter reaction times,
Bazureau, Jean-Pierre, Bentabed-Ababsa, Ghenia, Derdour, Aicha, Hamelin, Jack., Mongin, Florence, Rahmouni, Mustapha   +5 more
core   +2 more sources

A Novel Cycloaddition Reaction of Thermally Generated Sulfenes

CHIMIA, 1992
The highly strained ?-sultine 4, resulting from the addition of SO2 to benzobenzvalene, is shown to undergo a thermal cycloreversion which gives 1H-indene-1-thiocarbaldehyde dioxide (6) as an intermediate and subsequently 1H-indene-1 ...
Ulrich Burger, Serge P. Schmidlin, Jiri Mareda, Gerald Bernardinelli   +3 more
doaj   +2 more sources

SuFExable NH-Pyrazoles via 1,3-Dipolar Cycloadditions of Diazo Compounds with Bromoethenylsulfonyl Fluoride. [PDF]

J Org Chem, 2022
Yamanushkin P, Kaya K, Feliciano MAM, Gold B.   +3 more
europepmc   +1 more source

Acceleration of 1,3-Dipolar Cycloadditions by Integration of Strain and Electronic Tuning. [PDF]

J Am Chem Soc, 2021
Dones JM, Abularrage NS, Khanal N, Gold B, Raines RT.   +4 more
europepmc   +1 more source

Synthesis of 1,4-Disubstituted Mono and Bis-triazolocarbo-acyclonucleoside Analogues of 9-(4-Hydroxybutyl)guanine by Cu(I)-Catalyzed Click Azide-Alkyne Cycloaddition [PDF]

, 2011
A series of novel mono-1,2,3-triazole and bis-1,2,3-triazole acyclonucleoside analogues of 9-(4-hydroxybutyl)guanine was prepared via copper(I)-catalyzed 1,3-dipolar cycloaddition of N-9 propargylpurine, N-1-propargylpyrimidines/as-triazine with the ...
Engels, Joachim W., Krim, Jamal, Taourirte, Mohamed   +2 more
core   +2 more sources

Regio- and Diastereoselective 1,3-Dipolar Cycloadditions of 1,2,4-Triazin-1-ium Ylides: a Straightforward Synthetic Route to Polysubstituted Pyrrolo[2,1-f][1,2,4]triazines. [PDF]

ACS Omega, 2022
Galeta J, Šlachtová V, Dračínský M, Vrabel M.   +3 more
europepmc   +1 more source

Au(I)-catalyzed enantioselective 1,3-dipolar cycloadditions of münchnones with electron-deficient alkenes.

Journal of the American Chemical Society, 2007
The first catalytic enantioselective 1,3-dipolar cycloaddition of munchnone dipoles with electron-deficent alkenes is described. The reaction is catalyzed by chiral bis(phosphine)gold(I) benzoate complexes and provides Δ1-pyrrolines with excellent regio-,
Asa D. Melhado, M. Luparia, F. Toste
semanticscholar   +1 more source