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1,4-Dihydropyridines containing sulfur (review)
Chemistry of Heterocyclic Compounds, 1995The literature on the synthesis and reactions of monocyclic and polycyclic 1, 4-dihydropyridines containing sulfur in substituents or in the ring is reviewed.
Ya. Ozols, B. Vigante, G. Duburs
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CrysteEngComm, 2019
Halogen-substituted 1,4-dihydropyridine derivatives exhibit higher contrast mechanofluorochromic properties than the derivative without a halogen atom because of more twisted conformations and looser stacking arrangements.
Yating Chen +8 more
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Halogen-substituted 1,4-dihydropyridine derivatives exhibit higher contrast mechanofluorochromic properties than the derivative without a halogen atom because of more twisted conformations and looser stacking arrangements.
Yating Chen +8 more
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Vicinal diamination of 1,4-dihydropyridines
Chemical Communications, 1998Electrophilic interaction of iodine with N-alkyl-1,4-dihydropyridines 1 in the presence of secondary amines stereoselectively leads to the corresponding trans-2,3-diamino-1,2,3,4-tetrahydropyridines 2 in satisfactory yields (79–94%); the method allows the synthesis of piperidine, pyrrolidine, morpholine and piperazine derivatives.
Rodolfo Lavilla +4 more
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Reactions of 1,4-dihydropyridines (review)
Chemistry of Heterocyclic Compounds, 1993The literature published over the period 1986–1990 on the chemical properties (oxidation, addition, substitution, reactions of the functional groups, etc.) of 1,4-dihydropyridines is correlated.
A. Sausin'sh, G. Dubur
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Catalysis Today, 2017
A practical method is designated for the one-pot, multicomponent synthesis of 1,4-dihydropyridine derivatives by cyclo-condensation of aromatic aldehydes, 5,5-dimethyl-1,3-cyclohexanedione, acetoacetanilide and ammonium acetate.
S. V. Bhaskaruni +3 more
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A practical method is designated for the one-pot, multicomponent synthesis of 1,4-dihydropyridine derivatives by cyclo-condensation of aromatic aldehydes, 5,5-dimethyl-1,3-cyclohexanedione, acetoacetanilide and ammonium acetate.
S. V. Bhaskaruni +3 more
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One-Pot Assembly for Synthesis of 1,4-Dihydropyridine Scaffold and Their Biological Applications
Polycyclic aromatic compounds (Print), 2019A one-pot procedure for the preparation of functionalized 1,4-dihydropyridines by three-component reaction using substituted heterocyclic aldehydes, ammonium acetate, and substituted β-ketoesters catalyzed by L-proline was described.
Mayank G. Sharma +9 more
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The oxidation of 1,4-dihydropyridines
Chemistry of Heterocyclic Compounds, 1970The olefinic bond of methenylbisindan-1,3-dione, 2-benzylideneindan-1, 3-dione, and its derivatives is easily reduced by many 1, 4-dihydropyridines. Under the conditions described, other functional groups are untouched. These Β-dicarbonyl compounds are utilized to compare the effects of substituents in 1,4-dihydropyridines on their reactivity in the ...
G. Ya. Dubur, Ya. R. Uldrikis
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New Journal of Chemistry, 2019
A straightforward and efficient methodology for the synthesis of the medicinally important 1,4-dihydropyridines has been demonstrated using MIL-101-SO3H metal–organic framework as a sustainable Brønsted acid catalyst.
Nainamalai Devarajan, P. Suresh
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A straightforward and efficient methodology for the synthesis of the medicinally important 1,4-dihydropyridines has been demonstrated using MIL-101-SO3H metal–organic framework as a sustainable Brønsted acid catalyst.
Nainamalai Devarajan, P. Suresh
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Metalation of 1,4-dihydropyridine esters
Tetrahedron Letters, 1989Abstract 4-Aryl-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic esters are metalated at the NH and the C-2 methyl positions via tretament with two equivalents of n-butyl lithium. The resulting dilithio species can be treated with a variety of electrophiles to furnish C-2 methyl functionalized dihydropyridine esters.
Graham S. Poindexter +2 more
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The photochemistry of 3,5-disubstituted 1,4-dihydropyridines
Tetrahedron, 1970Abstract On irradiation, 1,4-dihydropyridines have been shown to undergo three types of reaction: disproportionation, isomerization and dimerization. The presence of 2,6-substituents inhibits these reactions except in the case of 3a which undergoes disproportionation.
U, Eisner +3 more
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