Results 241 to 250 of about 362,273 (289)

Far‐infrared irradiation attenuates platelet‐derived growth factor‐stimulated vascular smooth muscle cell migration through protein phosphatase 2A‐mediated Akt inhibition

Photochemistry and Photobiology, EarlyView.
FIR irradiation enhances the physical association between Akt and PP2Ac in VSMCs, independent of the hyperthermal effect of FIR rays. The increased binding between Akt and PP2Ac induced by FIR irradiation facilitates the dephosphorylation of Akt at Ser473.
Na‐Young Lee, Seo‐Hyeon Kim, Young Jin Kang, Il‐Kug Kim, Yun‐Jin Hwang, Du‐Hyong Cho   +5 more
wiley   +1 more source

The PI3K pathway is a downstream effector of NRF2 activation in the esophagus. [PDF]

Transl Oncol
Subramaniyan B, Li Y, Xiong Z, Paiboonrungruang C, Bui-Linh C, Spitz F, Chen X.   +6 more
europepmc   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

NGR1 Pretreatment Enhances the Therapeutic Efficacy of Transplanting Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells for Myocardial Infarction. [PDF]

Int J Mol Sci
Cai H, Huang MY, Mou FF, Wang QL, Luo ZR, Lu PP, Liu BN, Hu L, Guo HD.   +8 more
europepmc   +1 more source

NRBF2 homodimerization by its coiled-coil domain strengthens association with the PtdIns3K complex mediated by the MIT domain to promote autophagy. [PDF]

Autophagy
Li N, Li X, Qiu X, Pan X, Wu S, Chen J, Liu R, Lu J, Yue Z, Zhao Y.   +9 more
europepmc   +1 more source

Resistance exercise breaks during prolonged sitting augment the blood flow response to a subsequent oral glucose load in sedentary adults

Experimental Physiology, EarlyView.
Abstract Sitting‐induced impairments in postprandial blood flow are an important link between sedentary behaviour and cardiometabolic disease risk. The objective of this work was to examine the effects of resistance exercise breaks (REB) performed every 30 min during an otherwise sedentary 3‐h period on the vasodilatory response to a subsequent oral ...
Emily M. Rogers, Nile F. Banks, Emma R. Trachta, Morgan S. Wolf, Alexander C. Berry, Anna E. Stanhewicz, Lucas J. Carr, Bethany Barone Gibbs, Nathaniel D. M. Jenkins   +8 more
wiley   +1 more source

Metabolic reprogramming in neurodegenerative diseases: New insights into mTOR-mediated microglial polarization. [PDF]

J Transl Int Med
Song W, Zhang Y, Xu T, Fan T, Li J, Liu M, Wei W, Pei X, Li R.   +8 more
europepmc   +1 more source

ets-2 is a target for an akt (Protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant mice [PDF]

, 2000
Forsthoefel, D, Hartman, M, Hofmeister, J K, Hume, D A, Ostrowski, M C, Schaffner, A E, Smith, J L, Wei, G   +7 more
core  

Exercise training to preserve vitality capacity in ageing

Experimental Physiology, EarlyView.
Abstract Ageing is an escalating global health issue, with the World Health Organization (WHO) reporting that one in six individuals will be 60 years or older by the year 2030. Therefore, understanding the mechanisms of complex biological ageing processes and associated healthcare challenges has become increasingly important.
Raymond Jones, Taylor L. Taylor, Robert T. Mankowski, Fitzgerald Dodds, Michael Hankes, Joanna Hobson, Yi Lin, Keith Saffold, Silvienne C. Sint Jago, McKenna A. Tharpe, Emily L. Zumbro, Anna Thalacker‐Mercer, Thomas W. Buford   +12 more
wiley   +1 more source

Osimertinib acquired resistance among patients with EGFR-mutated NSCLC: from molecular mechanisms to clinical therapeutic strategies. [PDF]

Cancer Drug Resist
Wang R, Chen Y, Li L, Zhang L, Zhang S.
europepmc   +1 more source