Results 101 to 110 of about 1,499,618 (334)

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

Corporate Social Responsibility: An Application in Tourism Development in Ghana [PDF]

open access: yes, 2007
In 1972 UNESCO recognized 1) the Elmina Castle alias St George’s Castle located in Elmina, 2) the Fort St Jago located in Elmina, and 3) the Cape Coast Castle alias Carolsburg Castle located in Cape Coast as World Heritage Sites (slave dungeons during ...
Koutra, Christina
core  

Nudging Charitable Giving: The ethics of Nudge in international poverty reduction

open access: yesEthics & Global Politics, 2017
The use of nudge theory by non-governmental organizations and governments as a means to encourage charitable donations in order to address global poverty has been the subject of much recent enthusiasm.
Joshua Hobbs
doaj   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

open access: yesMolecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo   +8 more
wiley   +1 more source

Where are the poor in International Economics? [PDF]

open access: yes
Despite the fact that a very significant proportion of the human population is living with financial difficulties and other constraints typical of poverty, scientific studies in the areas of Economics and especially in International Economics that ...
Aurora A.C. Teixeira, Luis Carvalho
core  

Learning from the strengths of health care in schools in Brazil & opportunities for contemporary global school health

open access: yesGlobal Public Health
Most children and youth around the globe spend some time in school. Therefore, schools are essential for health, learning, and engaging families. School health models and programmes vary worldwide, some with strengths and weaknesses.
Lucine Francis   +2 more
doaj   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Do poorer countries have less capacity for redistribution ? [PDF]

open access: yes
Development aid and policy discussions often assume that poorer countries have less internal capacity for redistribution in favor of their poorest citizens. The assumption is tested using data for 90 developing countries.
Ravallion, Martin
core  

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