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Antibacterial Mechanism of 10-HDA Against Bacillus subtilis

2015
10-HDA (10-hydroxy-2-decenoic acid) is an unsaturated medium-chain fatty acid, which is the main active component of royal jelly. It has been shown to possess biological activity in antibacterial, immunoregulation, and antitumour. However, the underlying antibacterial mechanism of 10-HDA is unclear.
Xiaohui Yang, Junlin Li, Ruiming Wang
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Antibacterial Activity and Mechanism of Action of 10-HDA Against Escherichia coli

2013
10-HDA (10-hydroxy-2-decenoic acid), an unsaturated fatty acid, is the main active component of royal jelly. It has been demonstrated that 10-HDA possesses remarkable antibacterial activities. However, it is unclear in terms of the underlying antibacterial mechanism of 10-HDA.
Xiaohui Yang, Tengfei Wang, Ruiming Wang
openaire   +1 more source

Absence of 10-Hydroxy-2-Decenoic Acid (10-HDA) in Bee-Collected Pollen

1986
Much attention has been paid to the survival of bee-collected pollen in pellets as well as those sticking to body hairs. This interest stems from plant breeders concern to prevent contamination when using bees for pollination purposes in isolation cages on the one hand and, on the other hand, one would like to use bee-collected pollen to improve seed ...
Verhoef, H.C.M., Hoekstra, F.A.
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ARI SÜTÜ 10-HDA İÇERİĞİNİ ETKİLEYEN BAZI FAKTÖRLER

2023
Bal arılarının bitkisel üretimde tozlaşmaya olan katkısı bilinen bir gerçektir. Bunun yanında arıcılık faaliyetleri elde edilen ürünler hem işletmeye sağladığı gelir hem de insan sağlığına olan katkısı açısından önemli bir yere sahiptir. Her geçen gün kullanımı artan arı sütü, genç işçi arıların hipofarengeal ve mandibular bezlerinden salgılanan ...
Demir, Ferhat   +2 more
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[Determination of 10-HDA in honeybee body by HPLC].

Se pu = Chinese journal of chromatography, 2010
In the present work we found that in the honeybee body there exists an unsaturated fatty acid, trans-10-hydroxy-2-decenoic acid (10-HDA), which was known only to be present in royal jelly. We established the analytical method of 10-HDA in honeybee body by HPLC and simplified the extraction method of 10-HDA. In the optimum conditions the linear range of
H, Fan, C, He, H, Han
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Antioxidant activity and 10-HDA content in Lithuanian royal jelly

2020
Royal jelly is a natural bee product with great potential for use in medicine with many protein, free amino acids, carbohydrates, lipids, vitamins, minerals and phenolic compounds. Its wide chemical composition indicates that there are various bioactive substances such as 10-hydroxy-2-decenoic acid (10-HDA) [1].
Jestremskaitė, Greta   +3 more
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Functional and health properties of 10-HDA acid – a unique component of the royal jelly

58 Croatian and 18 International Symposium of Agriculture : Proceedings, 2023
Royal jelly is a special biologically active substance, with an extremely complex chemical composition, and is produced as a product of worker bees. The basic ingredient of royal jelly is 10-hydroxy-2-decenoic acid (10-HDA). It belongs to the group of unsaturated fatty acids and is not found anywhere in nature and cannot be synthesized.
openaire  

Preventive Effect of Royal Jelly and 10-HDA on Skin Damage in Diabetic Mice through Regulating Keratinocyte Wnt/β-Catenin and Pyroptosis Pathway

Molecular Nutrition and Food Research
The objective of this study is to elucidate how Royal jelly (RJ) and 10‐hydroxy‐2‐decanoic acid (10‐HDA) prevents diabetic skin dysfunction by modulating the pyroptosis pathway. Type 2 diabetes models are induced by fat diet consumption and low dose of streptozotocin (STZ) in C57BL/6J mice and treated with RJ (100 mg kg–1 day–1) and 10‐HDA, the major ...
Mingyang Zhang, Yumei An, Xinqi Huang
exaly   +3 more sources

Quantitative determination oftrans- 10-Hydroxy-2-Decenoic Acid (10-HDA) in Brazilian royal jelly and commercial products containing royal jelly

Journal of Apicultural Research, 2007
SummaryWe report the analysis of Brazilian commercial bee products using high performance liquid chromatography, and a faster method, to detect trans-10-Hydroxy-2-Decenoic Acid or 10-Hydroxy-2-E-decenoic acid (10-HDA) in royal jelly. Determination was carried out using aqueous phosphoric acid 0.1% (pH 2.5)/methanol (50/50) as the mobile phase, and a ...
Celira Caparica-Santos   +1 more
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The effects of 10-HDA on immune function of mice

European Journal of Pharmacology, 1990
J. Shi, S. Ling, W. Sun, H. Cai
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