Results 71 to 80 of about 326,549 (285)

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Breeding Better Flax (Linum Usitatissimum L.) for Agronomic and Consumption Values Under Different Field Treatments [PDF]

open access: yes, 2011
We studies some best levels of N fertilizer (0 to 150 kgha-1) and cultivation dates on grain yield its related characters and 5 food consumption compositions on 8 Linseed varieties at Yasooj Azad University, Iran, during 2009 and 2010 in field ...
Arminian, A. (Ali)   +2 more
core   +1 more source

The tumor–microbe connection

open access: yesMolecular Oncology, EarlyView.
Tumor‐associated bacteria (TAB) dynamically influence cancer biology by modulating tumor progression, metastatic spread, and therapeutic efficacy. Their presence redefines the tumor microenvironment (TME) as a microbial–host interface, yet mechanistic insights remain limited. Understanding TAB colonization routes, functional impacts, and crosstalk with
Gerlanda Vella, Maria Rescigno
wiley   +1 more source

SEVERAL ELEMENTS OF SEED PRODUCTIVITY IN CUCUMBER CULTIVARS BRED AT VNIISSOK

open access: yesОвощи России, 2017
Routine breeding work for cucumber cultivar and hybrid maintenance and their multiplication is carried out at Laboratory of Cucumber and Gourd Breeding and Seed Production, VNIISSOK.
I. B. Korotseva, L. A. Kochetkova
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Evaluation of Application Methods Efficiency of Zinc and Iron for Canola(Brassica napus L.)

open access: yesNotulae Scientia Biologicae, 2010
In order to evaluation of application method efficiency of zinc and iron microelements in canola, an experiment was conducted in the Agricultural Research Station of Eastern Azerbaijan province in 2008.
Ahmad BYBORDI, Garib MAMEDOV
doaj   +3 more sources

Yield and quality of soybean seeds as affected by growing conditions [PDF]

open access: yesRatarstvo i Povrtarstvo, 2011
Effect of environmental conditions (temperatures and precipitation) on soybean yield and seed quality was examined during two years. Trials with four replications were located at experimental fields of Institute of Field and Vegetable Crops at Rimski ...
Đukić Vojin   +6 more
doaj   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

open access: yesFEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová   +11 more
wiley   +1 more source

Character association and path analysis for yield and its related traits in finger millet (Eleusine coracana (L.) Gaertn) genotypes [PDF]

open access: yes, 2017
The present investigation was conducted during Kharif, 2014 at Research Block, Department of Crop Improvement, College of Forestry, Ranichauri Campus, V.C.S.G. Uttarakhand University of Horticulture and Forestry.
Bhatt, Arun   +2 more
core   +2 more sources

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