Results 101 to 110 of about 46,388,210 (340)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
PENINGKATAN HASIL BELAJAR DENGAN MENGGUNAKAN LKS BERBASIS PROBLEM BASED LEARNING PADA KONSEP JAMUR DI KELAS X [PDF]
, 2016 Penelitian ini dilatar belakangi dari hasil observasi dan wawancara di salah satu di sala h satu SMA Swasta di Kota Bandung yang menunjukan hasil belajar siswa pada mata pelajaran IPA - biologi tergolong rendah dengan salah satu faktor ...
LISTYA ANGRAINI, 12 50401 20
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
International physical activity questionnaire: 12-country reliability and validity.
Medicine & Science in Sports & Exercise, 2003 C. Craig +10 more
semanticscholar +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
, 2020 Another prime mover in the development of computers was cryptography – and in particular the breaking of German military codes during the second world war. It was this activity which really led to the modern computer era.
openaire +2 more sources
Significance and Educational Effects of Audio-Visual Aids Developed for Teaching Midwifery Technique in Integrated Curriculum [PDF]
, 2011 Journal Article統合カリキュラムの問題点をふまえ、統合カリキュラムにおける分娩介助技術法の視聴覚教材開発の意義と教育効果を明らかにすることを目的として、基礎教育であることをコンセプトに分娩介助技術法のDVDおよび解説書としてのテキストを作成し、講義・演習・実習を進めた。実習終了後に分娩期技術到達度自己評価および学生の自由記述式調査用紙の記載内容から分析を行った結果、学部教育の短期集中、2施設を移動する実習でも、介助例数を重ねながら段階を踏んで技術を習得することができていた。また、教員が創意・
11 +11 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source