Results 101 to 110 of about 45,682,230 (340)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

International physical activity questionnaire: 12-country reliability and validity.

open access: yesMedicine & Science in Sports & Exercise, 2003
C. Craig   +10 more
semanticscholar   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Significance and Educational Effects of Audio-Visual Aids Developed for Teaching Midwifery Technique in Integrated Curriculum [PDF]

open access: yes, 2011
Journal Article統合カリキュラムの問題点をふまえ、統合カリキュラムにおける分娩介助技術法の視聴覚教材開発の意義と教育効果を明らかにすることを目的として、基礎教育であることをコンセプトに分娩介助技術法のDVDおよび解説書としてのテキストを作成し、講義・演習・実習を進めた。実習終了後に分娩期技術到達度自己評価および学生の自由記述式調査用紙の記載内容から分析を行った結果、学部教育の短期集中、2施設を移動する実習でも、介助例数を重ねながら段階を踏んで技術を習得することができていた。また、教員が創意・
11   +11 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

University High Highlights 12/12/1962 [PDF]

open access: yes, 1962
This is the student newspaper from University High School, the high school that was on the campus of Western Michigan University, then called University High Highlights, in ...
, University High School
core   +1 more source

12 Ciphers

open access: yes, 2020
Another prime mover in the development of computers was cryptography – and in particular the breaking of German military codes during the second world war. It was this activity which really led to the modern computer era.
openaire   +2 more sources

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