Erythropoietin messenger RNA levels in developing mice and transfer of 125I-erythropoietin by the placenta. [PDF]
J Clin Invest, 1988 Erythropoietin (EP) mRNA was measured in normal and anemic mice during fetal and postnatal development. Normal fetal livers at 14 d of gestation contained a low level of EP mRNA. By day 19 of gestation, no EP mRNA was detected in normal or anemic fetal livers or normal fetal kidneys, but anemic fetal kidneys had low levels of EP mRNA.
Koury MJ +3 more
europepmc +5 more sources
Synthesis and biological evaluation of 125I-erythropoietin as a potential radiopharmaceutical agent for tumours [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2011 Erythropoietin (EPO) is a glycoprotein hormone responsible for regulating erythropoiesis. Expression of EPO and EPO receptors (EPOr) has recently been demonstrated in some neoplastic cell lines and tumours, suggesting a potential new target for therapy ...
Gonçalo dos Santos Clemente +1 more
doaj +8 more sources
Erythropoietin promoted the proliferation of hepatocellular carcinoma through hypoxia induced translocation of its specific receptor [PDF]
Cancer Cell International, 2017 Background Erythropoietin (EPO) is a hypoxia-inducible stimulator of erythropoiesis. Besides its traditional application in anemia therapy, it offers an effective treatment in the cancer patients, especially those who receive chemotherapy.
Shuo Miao +8 more
doaj +2 more sources
Validation of a clinically applicable device for fast and accurate quantification of blood volume. [PDF]
J Clin Lab Anal, 2023 The cumbersome nature of the dual‐isotope (e.g., 99mTc and 125I‐HSA) injection method has limited the widespread use of blood volume (BV) evaluation in medicine. However, BV has been determined in laboratory settings for centuries using a reliable and rapid carbon monoxide (CO)‐rebreathing‐based procedure.
Breenfeldt Andersen A +4 more
europepmc +2 more sources
Binding of recombinant human 125I-erythropoietin to CFU-E from the spleen of anemic mice.
Haematologica, 1990 Erythroid precursors were obtained from the spleen of mice made anemic with phenylhydrazine and used to study the binding of bioactive 125I-rEp to membrane receptors. Kinetic analysis, using splenic cells obtained at different times following the induction of anemia, showed that the maximum binding was reached at day 3, and decreased thereafter ...
VANNUCCHI, ALESSANDRO MARIA +4 more
openaire +3 more sources
A Putative Single-Photon Emission CT Imaging Tracer for Erythropoietin-Producing Hepatocellular A2 Receptor. [PDF]
ACS Med Chem Lett, 2021 Furukawa T +6 more
europepmc +1 more source
Stimuli-responsive polypeptide nanogels for trypsin inhibition. [PDF]
Beilstein J Nanotechnol, 2022 Šálek P +6 more
europepmc +1 more source
Treatment of Parkinson's disease with biologics that penetrate the blood-brain barrier via receptor-mediated transport. [PDF]
Front Aging Neurosci, 2023 Pardridge WM.
europepmc +1 more source
Isolation and evaluation of erythroid progenitors in the livers of larval, froglet, and adult Xenopus tropicalis. [PDF]
Biol Open, 2023 Omata K +8 more
europepmc +1 more source
Pharmacokinetics of Biopharmaceuticals: Their Critical Role in Molecular Design. [PDF]
Biomedicines, 2023 Ogihara T, Mizoi K, Ishii-Watabe A.
europepmc +1 more source