Results 11 to 20 of about 47 (43)

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Catalytic receptors

open access: yesBritish Journal of Pharmacology, Volume 176, Issue S1, Page S247-S296, December 2019., 2019
The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www ...
Stephen P H Alexander   +20 more
wiley   +1 more source

Abstracts

open access: yes, 2021
Research and Practice in Thrombosis and Haemostasis, Volume 5, Issue S2, October 2021.
wiley   +1 more source

Effects of the sodium‐glucose co‐transporter‐2 inhibitor dapagliflozin on estimated plasma volume in patients with type 2 diabetes

open access: yesDiabetes, Obesity and Metabolism, Volume 21, Issue 12, Page 2667-2673, December 2019., 2019
Abstract Aims To compare the effects of the sodium‐glucose co‐transporter‐2 (SGLT2) inhibitor dapagliflozin on estimated (ePV) and measured plasma volume (mPV) and to characterize the effects of dapagliflozin on ePV in a broad population of patients with type 2 diabetes.
Claire C. J. Dekkers   +5 more
wiley   +1 more source

When hemolysis masks polycythemia vera

open access: yesClinical Case Reports, Volume 7, Issue 3, Page 438-441, March 2019., 2019
Although uncommon, clinicians should be aware that polycythemia vera may be masked due to hemolysis. The report of such associations could help them in clinical practice to establish an early and accurate diagnosis that may be challenging in atypical presentations of myeloproliferative neoplasms.
Coralie Derrieux   +5 more
wiley   +1 more source

Emerging nanoprobes for the features visualization of vulnerable atherosclerotic plaques

open access: yesSmart Medicine, Volume 3, Issue 4, December 2024.
The pathophysiology of atherosclerosis and the rational design principle of nanoprobes for the feature visualization of vulnerable atherosclerotic plaques are introduced. In addition, the nanoprobes for the feature visualization of vulnerable atherosclerotic plaques are discussed. Abstract Atherosclerosis (AS) is a major cause of cardiovascular disease.
Xin Wang   +7 more
wiley   +1 more source

Noncanonical IFN Signaling, Steroids, and STATs: A Probable Role of V‐ATPase

open access: yesMediators of Inflammation, Volume 2019, Issue 1, 2019., 2019
A small group of only seven transcription factors known as STATs (signal transducer and activator of transcription) are considered to be canonical determinants of specific gene activation for a plethora of ligand/receptor systems. The activation of STATs involves a family of four tyrosine kinases called JAK kinases.
Howard M. Johnson   +3 more
wiley   +1 more source

Haemodynamic, hormonal and renal actions of osteocrin in normal sheep

open access: yesExperimental Physiology, Volume 109, Issue 8, Page 1305-1316, 1 August 2024.
Abstract Osteocrin (OSTN) is an endogenous protein sharing structural similarities with the natriuretic peptides [NPs; atrial (ANP), B‐type (BNP) and C‐type (CNP) NP], which are hormones known for their crucial role in maintaining pressure/volume homeostasis. Osteocrin competes with the NPs for binding to the receptor involved in their clearance (NPR‐C)
Nicola J. A. Scott   +5 more
wiley   +1 more source

Serum gastrin concentrations in dogs with primary hyperparathyroidism

open access: yesJournal of Veterinary Internal Medicine, Volume 38, Issue 1, Page 123-129, January/February 2024.
Abstract Background Hypercalcemia has been associated with hypergastrinemia in humans. Hypergastrinemia could be responsible for gastrointestinal (GI) signs in dogs with primary hyperparathyroidism (PHPT). Hypothesis/Objectives (a) Determine whether hypergastrinemia occurs in dogs with PHPT, (b) assess for potential correlations among ionized calcium ...
Julieann Vose   +9 more
wiley   +1 more source

Investigation into experimental toxicological properties of plant protection products having a potential link to Parkinson's disease and childhood leukaemia

open access: yesEFSA Journal, Volume 15, Issue 3, March 2017., 2017
Abstract In 2013, EFSA published a literature review on epidemiological studies linking exposure to pesticides and human health outcome. As a follow up, the EFSA Panel on Plant Protection Products and their residues (PPR Panel) was requested to investigate the plausible involvement of pesticide exposure as a risk factor for Parkinson's disease (PD) and
EFSA Panel on Plant Protection Products and their residues (PPR)   +34 more
wiley   +1 more source

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