Results 101 to 110 of about 38,521 (297)

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

open access: yesAdvanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro   +6 more
wiley   +1 more source

In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases

open access: yesAdvanced Science, EarlyView.
This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du   +6 more
wiley   +1 more source

Experimental flux measurements on a network scale

open access: yesFrontiers in Plant Science, 2011
Metabolic flux is a fundamental property of living organisms. In recent years, methods for measuring metabolic flux in plants on a network scale have evolved further.
Jörg eSchwender
doaj   +1 more source

Global 13C tracing and metabolic flux analysis of intact human liver tissue ex vivo

open access: yesNature Metabolism
Liver metabolism is central to human physiology and influences the pathogenesis of common metabolic diseases. Yet, our understanding of human liver metabolism remains incomplete, with much of current knowledge based on animal or cell culture models that ...
Nina Grankvist   +11 more
semanticscholar   +1 more source

Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism

open access: yesAdvanced Science, EarlyView.
Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards   +8 more
wiley   +1 more source

13 C-MFA helps to identify metabolic bottlenecks for improving malic acid production in Myceliophthora thermophila

open access: yesMicrobial Cell Factories
Background Myceliophthora thermophila has been engineered as a significant cell factory for malic acid production, yet strategies to further enhance production remain unclear and lack rational guidance.
Junfeng Jiang   +5 more
doaj   +1 more source

13C metabolic flux analysis-guided metabolic engineering of Escherichia coli for improved acetol production from glycerol

open access: yesBiotechnology for Biofuels, 2019
Background Bioprocessing offers a sustainable and green approach to manufacture various chemicals and materials. Development of bioprocesses requires transforming common producer strains to cell factories.
Ruilian Yao   +4 more
doaj   +1 more source

Bomb-14C analysis of ecosystem respiration reveals that peatland vegetation facilitates release of old carbon [PDF]

open access: yes, 2009
The largest terrestrial-to-atmosphere carbon flux is respired CO<sub>2</sub>. However, the partitioning of soil and plant sources, understanding of contributory mechanisms, and their response to climate change are uncertain.
A.E. Fallick   +90 more
core   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

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