Results 151 to 160 of about 38,521 (297)

Focusing on \u201cthe important\u201d through targeted NMR experiments: An example of selective 13C-12C bond detection in complex mixtures [PDF]

open access: yes, 2018
Bermel, Wolfgang   +6 more
core   +1 more source

Degradable Nanocarriers Capable of Gene Delivery Derived from pH‐Responsive Polyester: RROP Copolymerization Between Cyclic Ketene Acetals

open access: yesMacromolecular Rapid Communications, EarlyView.
Polyesters with inherent pH‐sensitivity are prepared through radical ring‐opening polymerization between cyclic ketene acetals. These polyesters demonstrate great potential as alternatives to conventional polycations for fabricating hybrid nanoparticles.
Yiyi Deng   +3 more
wiley   +1 more source

Spatial patterns of hepatocyte glucose flux revealed by stable isotope tracing and multi-scale microscopy

open access: yesNature Communications
Metabolic homeostasis requires engagement of catabolic and anabolic pathways consuming nutrients that generate and consume energy and biomass. Our current understanding of cell homeostasis and metabolism, including how cells utilize nutrients, comes ...
Aliyah Habashy   +16 more
doaj   +1 more source

Multi‐Solvent Suppression Ultrafast 2D COSY for High‐Throughput Wine Screening

open access: yesMagnetic Resonance in Chemistry, EarlyView.
An interleaved ultrafast COSY with multi‐solvent suppression was developed for wine analysis to overcome limitations often associated with 1D 1H NMR (signal overlap) and conventional 2D NMR (long acquisition times) methods. Within an acquisition time of ~20 min, it revealed hidden metabolite peaks and cross peaks for improved annotation and ...
Pia S. Mayer   +5 more
wiley   +1 more source

Deuterium 1‐Channel Transmit/16‐Channel High Impedance Receive Array Combined With 16‐Channel 1H Dual‐Row Transceiver Array for 7 Tesla Brain Imaging

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop and evaluate an 2H/1H coil configuration that enables deuterium metabolic imaging at 7 T while preserving high‐quality 1H anatomical imaging. Methods An 16‐channel 2H high‐impedance receive array was combined with a 2H transmit birdcage and a 16‐channel dual‐row 1H transceiver array.
Bei Zhang   +3 more
wiley   +1 more source

The effects of seasonality and parasitism on diet and habitat selection in the common periwinkle

open access: yesOikos, EarlyView.
The common periwinkle Littorina littorea is an ecologically important grazer, known for its strong influence on algal communities and its role in structuring ecosystems. It serves as the first intermediate host for several trematode species in the Baltic Sea, especially for the fluke Cryptocotyle lingua.
Friederike Gronwald   +7 more
wiley   +1 more source

Modifying Antibiotic Activity of Synthetic Thiadiazine Analogs Against MDR Bacteria and ADMET Analysis

open access: yesChemistryOpen, EarlyView.
The study demonstrated that thidiazine compounds potentiated the action of antibiotics. The compounds associated with norfloxacin against S. aureus showed greater significance in relation to the other medications. The indiscriminate use of antibiotics has led to the selection of resistant bacterial strains, significantly reducing the effectiveness of ...
João Arthur de Oliveira Borges   +15 more
wiley   +1 more source

Computational Study on Potentially Active Antibacterial Compounds in Secondary Metabolites of Extremophilic Microorganisms

open access: yesChemistryOpen, EarlyView.
This study employed density functional theory (DFT) and conceptual DFT (CDFT) to calculate the structures and properties of potential antibacterial compounds derived from 16‐membered lactone ring‐containing secondary metabolites of extremophiles, as well as midecamycin.
Dilong Li   +6 more
wiley   +1 more source

Development of a Sustainable Biocatalytic Process for Geranyl Benzoate Production Using Immobilized Lipase

open access: yesChemistryOpen, EarlyView.
This study optimized solvent‐free geranyl benzoate production using Lipozyme 435, achieving 72% conversion in 6 hours. Open reactors improved yields (>99% in 48 hours) by removing inhibitorymethanol. Methyl benzoate reduced enzyme activity by 54%, though Lipura Flex showed better resistance. Human cell tests confirmed no cytotoxicity.
Domenico Meola   +9 more
wiley   +1 more source

Cyanoacetamidobetaine—A Zwitterionic Nitrile Derivative

open access: yesChemistryOpen, EarlyView.
The reaction of sodium dicyanamide with betainium chloride in aqueous solution affords N‐cyano‐2‐(trimethylammonio)acetaminide (cyanoacetamidobetaine). Single crystal X‐ray diffraction reveals a monoclinic structure comprising a trimethylammonium head group connected to a cyanoacetaminide unit via a methylene bridge.
Pan Duan   +5 more
wiley   +1 more source

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