Results 191 to 200 of about 38,521 (297)

Monochorionic-twin-on-a-chip for investigating fetal organ growth and metabolism. [PDF]

Microsyst Nanoeng
Ran R, Dong X, Yang Y, Shakeel S, Liu X, Saffery R, Yang J, Han TL.   +7 more
europepmc   +1 more source

Dual action of imeglimin on insulin secretion and sensitivity in type 2 diabetes

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Imeglimin is a novel oral hypoglycemic agent approved for the treatment of type 2 diabetes in Japan, with dual actions to enhance insulin secretion and improve insulin sensitivity, suggested by preclinical evidence. However, the effect of imeglimin on tissue‐specific insulin sensitivity and glucose kinetics using glucose tracers is ...
Tsubasa Tajima, Hideyoshi Kaga, Naoaki Ito, Toshiki Kogai, Hitoshi Naito, Saori Kakehi, Satoshi Kadowaki, Yuya Nishida, Ryuzo Kawamori, Yoshifumi Tamura, Hirotaka Watada   +10 more
wiley   +1 more source

Phase-driven rewiring in Escherichia coli enhances coenzyme Q10 biosynthesis via temporal and energetic coordination. [PDF]

Appl Microbiol Biotechnol
Li H, Wu Y, Qin D, Xie J, Huang W, Chen R, Liu H, Wang Y, Zhao D.   +8 more
europepmc   +1 more source

Deciphering the properties and reaction mechanism of anhydromevalonate phosphate decarboxylase, a prenylated flavin mononucleotide‐dependent enzyme in the archaeal mevalonate pathway

The FEBS Journal, EarlyView.
Characterization of anhydromevalonate phosphate decarboxylase, the UbiD‐family decarboxylase involved in the archaeal mevalonate pathway, was conducted. The enzyme is responsible for the biosynthesis of isoprenoids, such as archaeal membrane lipids, respiratory quinones, and dolichols.
Rino Ishikawa, Natsumi Matsushima, Soma Ishimine, Honoka Nakamoto, Hajime Hayakawa, Yoko Yasuno, Tetsuro Shinada, Hiroshi Kawaide, Tomokazu Ito, Hisashi Hemmi   +9 more
wiley   +1 more source

Dodecanedioic Acid: Alternative Carbon Substrate or Toxic Metabolite? [PDF]

Biomolecules
Radzikh I, Oyarbide U, Patil AS, Sandlers YI.   +3 more
europepmc   +1 more source

Quantitative differences in anaerobic growth and metabolism of three different E. coli strains using 13C-Metabolic Flux Analysis

bioRxiv
Piyush Pachauri, T. Desai, Ahmad Ahmad, S. Srivastava   +3 more
semanticscholar   +1 more source

Age‐Dependent Increase in Small Intestinal Permeability and Sex‐Dependent Absorptive Capacity in Cats (Felis catus)

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Age‐associated changes in intestinal permeability and function have not been studied in domestic cats, leaving a key factor in the relationship between age and digestive health in cats unexplored. Due to factors not currently understood, mature and senior cats may experience a loss of fat and protein digestibility, along with a loss of body ...
Keely Patterson, Emma N. Bermingham, Karl Fraser, Daniel Bernstein, Karin Weidgraaf, Anna K. Shoveller, David G. Thomas   +6 more
wiley   +1 more source

Synthetic Biology and Metabolic Engineering of Microalgae for Sustainable Lipid and Terpenoid Production: An Updated Perspective

Plant Biotechnology Journal, EarlyView.
ABSTRACT Microalgae are increasingly recognised as powerful platforms for the sustainable production of lipids and terpenoids, with expanding applications in the food, fuel and biomanufacturing industries. In this updated review, we consolidate and critically assess the most recent advances in synthetic biology and metabolic engineering of key ...
Ty Shitanaka, Yu Wang, Sally Do, Julia Yuson, Samir Kumar Khanal, Krzysztof Zienkiewicz, Zhi‐Yan Du   +6 more
wiley   +1 more source

Non-invasive visualisation of long-lasting brain metabolic alterations in murine pseudo-infection model using parahydrogen-polarised [1-¹³C] pyruvate MRI. [PDF]

Discov Nano
Tomiyama H, Yamasaki M, Isagawa T, Takeda N, Hashimoto T, Hirata H, Matsumoto S.   +6 more
europepmc   +1 more source

Central metabolic responses to the overproduction of fatty acids in Escherichia coli based on 13C‐metabolic flux analysis

Biotechnology and Bioengineering, 2014
Lian He, Yi Xiao, Nikodimos A Gebreselassie, Fuzhong Zhang, M. Antoniewicz, Yinjie J. Tang, Lifeng Peng   +6 more
semanticscholar   +1 more source