Results 41 to 50 of about 38,521 (297)
bioRxiv, 2021 13C-Metabolic flux analysis (13C-MFA) have greatly contributed to revealing the regulation of plant metabolism. However, mass spectrometry (MS) approaches have hitherto been limited in their power to deduce flux information due to lack of positional ...
André G. Daubermann +7 more
semanticscholar +1 more source
FluxPyt: a Python-based free and open-source software for 13C-metabolic flux analyses [PDF]
PeerJ, 2018 13C-Metabolic flux analysis (MFA) is a powerful approach to estimate intracellular reaction rates which could be used in strain analysis and design.
Trunil S. Desai, Shireesh Srivastava
doaj +2 more sources
Fructose metabolism in Chromohalobacter salexigens: interplay between the Embden–Meyerhof–Parnas and Entner–Doudoroff pathways [PDF]
, 2019 Background The halophilic bacterium Chromohalobacter salexigens metabolizes glucose exclusively through the Entner–Doudoroff (ED) pathway, an adaptation which results in inefficient growth, with significant carbon overflow, especially at low salinity ...
Argandoña Bertrán, Montserrat +12 more
core +1 more source
Updates in metabolomics tools and resources: 2014-2015 [PDF]
, 2016 Data processing and interpretation represent the most challenging and time-consuming steps in high-throughput metabolomic experiments, regardless of the analytical platforms (MS or NMR spectroscopy based) used for data acquisition.
Misra, Biswapriya B. +1 more
core +1 more source
bioRxiv, 2023 The pentose phosphate pathway (PPP) plays a key role in the cellular regulation of immune cell function; however, little is known about the interplay of metabolic adjustments in granulocytes, especially regarding the non-oxidative PPP.
Melanie Hogg +5 more
semanticscholar +1 more source
Stable isotope metabolomics of pulmonary artery smooth muscle and endothelial cells in pulmonary hypertension and with TGF-beta treatment. [PDF]
, 2020 Altered metabolism in pulmonary artery smooth muscle cells (PASMCs) and endothelial cells (PAECs) contributes to the pathology of pulmonary hypertension (PH), but changes in substrate uptake and how substrates are utilized have not been fully ...
D' Alessandro, Angelo +12 more
core +1 more source
Serine one-carbon catabolism with formate overflow [PDF]
, 2016 Serine catabolism to glycine and a one-carbon unit has been linked to the anabolic requirements of proliferating mammalian cells. However, genome-scale modeling predicts a catabolic role with one-carbon release as formate. We experimentally prove that in
Athineos, Dimitris +11 more
core +1 more source
Bioengineering, 2015 Metabolic engineering of various industrial microorganisms to produce chemicals, fuels, and drugs has raised interest since it is environmentally friendly, sustainable, and independent of nonrenewable resources.
Weihua Guo, Jiayuan Sheng, Xueyang Feng
doaj +1 more source
Metabolic networks in motion: 13 C‐based flux analysis [PDF]
Molecular Systems Biology, 2006 Many properties of complex networks cannot be understood from monitoring the components--not even when comprehensively monitoring all protein or metabolite concentrations--unless such information is connected and integrated through mathematical models.
openaire +2 more sources
Imaging glutathione depletion in the rat brain using ascorbate-derived hyperpolarized MR and PET probes. [PDF]
, 2018 Oxidative stress is a critical feature of several common neurologic disorders. The brain is well adapted to neutralize oxidative injury by maintaining a high steady-state concentration of small-molecule intracellular antioxidants including glutathione in
Carroll, Valerie N +10 more
core +1 more source