Results 71 to 80 of about 38,521 (297)
Partial (13)C isotopic enrichment of nucleoside monophosphates: useful reporters for NMR structural studies [PDF]
, 2005 Analysis of the (13)C isotopic labeling patterns of nucleoside monophosphates (NMPs) extracted from Escherichia coli grown in a mixture of C-1 and C-2 glucose is presented. By comparing our results to previous observations on amino acids grown in similar
Kishore, Anita I. +2 more
core +2 more sources
Rapid in situ 13C tracing of sucrose utilization in Arabidopsis sink and source leaves
Plant Methods, 2017 Background Conventional metabolomics approaches face the problem of hidden metabolic phenotypes where only fluxes are altered but pool sizes stay constant. Metabolic flux experiments are used to detect such hidden flux phenotypes.
Frederik Dethloff +2 more
doaj +1 more source
Metabolite concentrations, fluxes and free energies imply efficient enzyme usage. [PDF]
, 2016 In metabolism, available free energy is limited and must be divided across pathway steps to maintain a negative ΔG throughout. For each reaction, ΔG is log proportional both to a concentration ratio (reaction quotient to equilibrium constant) and to a ...
Amador-Noguez, Daniel +6 more
core +2 more sources
13C-metabolic flux analysis in glycerol-assimilating strains of Saccharomyces cerevisiae.
Journal of General and Applied Microbiology, 2021 Glycerol is an attractive raw material for the production of useful chemicals using microbial cells. We previously identified metabolic engineering targets for the improvement of glycerol assimilation ability in Saccharomyces cerevisiae based on adaptive
Taiji Yuzawa +5 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.Despite significant efforts in developing novel biomaterials to regenerate tissue, only a few of them have successfully reached clinical use. It has become clear that the next generation of biomaterials must be multifunctional. Smart biomaterials can respond to environmental or external stimuli, interact in a spatial‐temporal manner, and trigger ...
Sonya Ghanavati +12 more
wiley +1 more source
Investigation into the flux distribution of central carbon metabolism in Corynebacterium glutamicum using principal component analysis [PDF]
Archives of Biological Sciences, 2015 Central carbon metabolism is the main source of energy required by organisms and it provides precursors for other in vivo metabolic processes.
Shang Chuanyu +4 more
doaj +1 more source
What do cells actually want? [PDF]
, 2016 Genome-scale models require an objective function representing what an organism strives for. A method has been developed to infer this fundamental biological function from data.Please see related Research article: www.dx.doi.org/10.1186/s13059-016-0968 ...
Feist, Adam M, Palsson, Bernhard O
core +3 more sources
, 2020 Crabtree effect is well known for Saccharomyces cerevisiae, and is defined as glucose-induced repression of respiratory flux. Even though a number of hypotheses have been formulated, its triggering mechanisms are still unknown.
Huan Li +4 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji +8 more
wiley +1 more source
Flux-balance modelling of plant metabolism
Frontiers in Plant Science, 2011 Flux-balance modelling of plant metabolic networks provides an important complement to 13C-based metabolic flux analysis. Flux-balance modelling is a constraints-based approach in which steady-state fluxes in a metabolic network are predicted by using ...
Lee James Sweetlove +1 more
doaj +1 more source