Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Quelles techniques pour végétaliser des enrochements de berges de cours d’eau ? [PDF]
Les enrochements de berge de rivière constituent un pis-aller sur le plan environnemental et le génie végétal lui est préférable. Toutefois, lorsque les contraintes imposent d’avoir recours à des enrochements, il est préférable de les végétaliser pour ...
EVETTE, André +4 more
doaj
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Telecom O-Band Quantum Dots Fabricated by Droplet Etching
We present a novel growth technique for fabricating low-density InAs/GaAs quantum dots that emit in the telecom O-band. This method combines local droplet etching on GaAs surfaces using gallium with Stranski–Krastanov growth initiated by InAs deposition.
Nikolai Spitzer +7 more
doaj +1 more source
Xian, Peixin (2018): Die Bedeutung kultureller Differenzen für die soziale Interaktion. Von chinesischen und deutschen Tabus zur Kommunikationsstrategie in der wirtschaftlichen Interaktion zwischen Deutschen und Chinesen. München: iudicium, 2018. – ISBN 978-3-86205-523-4. 150 Seiten, € 24,00. [PDF]
Xiaoling Zhang
openalex +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Production Practice of 150 mm×150 mm Concasting Billet of Steel ML08Al
The low carbon low silicon aluminum killed steel ML08Al(%:≤0.08C,0.20~0.50Mn,≤0.06Si, 0.02Al)was produced by 83 t top-bottom combined blown converter - 83 t ladle furnace - 6 strand 150 mmx 150 mm billet concaster process at Baotou Steel.
郭平, 郑颖, 石玉宏
doaj
ICRP Publication 150: Cancer Risk from Exposure to Plutonium and Uranium
M. Tirmarche +10 more
openalex +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source

