Results 41 to 50 of about 107,971,354 (204)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Ilustracja Polska (1901–1904): Poland’s first modern illustrated weekly [PDF]
, 2017 Artykuł stanowi pionierską próbę przedstawienia sylwetki czasopisma „Ilustracja Polska” — pierwszego nowoczesnego polskiego tygodnika ilustrowanego, poświęconego chwili bieżącej (jednocześnie pierwszego tego typu magazynu w Galicji).
Wulczyńska, Magdalena
core
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The programme and thematic range of the Polish Newspaper in Berlin (Gazeta Polska w Berlinie) [PDF]
, 2016 Gazeta Polska w Berlinie was launched at the end of the 19th century, a time when the Polish migrant community in Berlin became sufficiently strong to be able to support its own newspaper.
Kędzierska, Sylwia
core
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
, 1985 S\u142owa kluczowe: post\u119powanie cywilne \u2013 historia \u2013 Polska \u2013 16-18 w.; s\u105downictwo \u2013 Polska \u2013 16-18 w.; Gda\u144sk \u2013 prawo \u2013 historia \u2013 16-18 w.; stosunki pa\u144stwo \u2013 Ko\u15bci\uf3\u142; rola ...
Rymaszewski, Zygfryd
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Narodowy Plan Rozwoju Polski 2007-2013 w świetle polityki spójności Unii Europejskiej [PDF]
, 2004 Zdigitalizowano i udostępniono w ramach projektu pn. Rozbudowa otwartych zasobów naukowych Repozytorium Uniwersytetu w Białymstoku, dofinansowanego z programu „Społeczna odpowiedzialność nauki” Ministra Edukacji i Nauki na podstawie umowy SONB/SP/512497 ...
Proniewski, Marek
core