Results 61 to 70 of about 4,477 (209)

Polacy w zaraniu Stan\uf3w Zjednoczonych [PDF]

, 1992
S\u142owa kluczowe: historia Stan\uf3w Zjednoczonych (18-19 w.); zwi\u105zki polsko-ameryka\u144skie w 17 i 18 w.; Polacy za granic\u105 \u2013 Stany Zjednoczone; Stany Zjednoczone a Polska w 18 w.; Mieczys\u142aw Haiman (1888 ...
Pastusiak, Longin
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USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Mi\u119dzy spo\u142ecze\u144stwem szlacheckim a w\u142adz\u105: problemy komunikacji spo\u142eczno\u15bci lokalne \u2013 w\u142adza w epoce Jana Kazimierza

, 2002
S\u142owa kluczowe: wojny \u2013 Polska (16-17 w.); Jan II Kazimierz Waza (1609-1972); relacja w\u142adza centralna a spo\u142eczno\u15b\u107 lokalna: Polska \u2013 Anglia (16-17 w.); Sejm polski i szlachta polska (16-17 w.); komunikacja spo\u142eczna w ...
Choi\u144ska-Mika, Jolanta
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Influence of functional groups of polystyrene-divinylbenzene adsorbents on the effectiveness of acid dye removal [PDF]

, 2019
For removal of C.I. Acid Red 18 (cochineal red A, ponceau 4R) from aqueous solutions, polystyrene Amberlyst A 21 and Lewatit VPOC 1064 were used. C.I. Acid Red 18 sorption was performed using static and dynamic methods.
Wawrzkiewicz, Monika, Polska-Adach, Ewelina   +1 more
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Instytut Badawczy Dróg i Mostów na targach AUTOSTRADA-POLSKA

, 2012
Zakończyła się 18. edycja Międzynarodowych Targów Budownictwa Drogowego AUTOSTRADA-POLSKA. Tej rangi spotkanie przedstawicieli branży drogowej nie mogło odbyć się bez udziału Instytutu Badawczego Dróg i Mostów z Warszawy.
Janiszewska, E.
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Prasa krakowska na warsztatach historyków : próba syntetycznego spojrzenia [PDF]

, 2012
Article includes a systematic review of the achievements of research on the history of the press in ...
Kolasa, Władysław Marek
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Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Kompetencje kulturowe w opiece zdrowotnej [PDF]

, 2019
Polska, w związku z przystąpieniem do Unii Europejskiej, stała się państwem bardziej zróżnicowanym kulturowo. Ma to wpływ na wiele sfer życia społecznego, w tym na opiekę medyczną.
Przyłęcki, Paweł
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