Results 91 to 100 of about 1,724,626 (297)

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Enabling Power System Restoration from Offshore Wind Power Plants in the UK

open access: yesEnergies
This paper presents the findings from the initial phases of the SIF BLADE project, focused on demonstrating the capabilities of an offshore wind power plant (OWPP) for power system restoration (PSR).
Rui Alves   +3 more
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Židovski hodočasnici na hrvatskoj obali Jadrana (15. – 16. st.)

open access: yesRadovi Zavoda za povijesne znanosti HAZU u Zadru, 2019
U radu su analizirani tekstovi židovskih hodočasnika koji su u razdoblju od prve polovice 15. do druge polovice 16. st. prošli hrvatskom obalom Jadrana na putu u Erec Izrael. Obrađeni su motivi putovanja, imovinsko stanje i zanimanje te odnos sredine u kojoj su boravili kao pripadnici talijanske zajednice aškenaza.
openaire   +4 more sources

St. John's Daily News, 1861-08-16

open access: yes
Published in St. John's from 27 August 1860 - 21 July 1870, the St. John's Daily News reported local and international news daily except Sunday for most of its run, reducing to three times a week after February ...

core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

St. John's Daily News, 1861-01-16

open access: yes
Published in St. John's from 27 August 1860 - 21 July 1870, the St. John's Daily News reported local and international news daily except Sunday for most of its run, reducing to three times a week after February ...

core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

St. John's Daily News, 1860-10-16

open access: yes
Published in St. John's from 27 August 1860 - 21 July 1870, the St. John's Daily News reported local and international news daily except Sunday for most of its run, reducing to three times a week after February ...

core  

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