Results 81 to 90 of about 1,724,626 (297)
Endothelin-1 Production by Normal Human Cultured Keratinocytes and its Regulation
Mediators of Inflammation, 1994 The possibility that cultured keratinocytes produce endothelins were investigated. The results showed that cultured keratinocytes derived from normal human skin produce endothelin-1. Moreover, keratinocyte endothelin-1 production was completely inhibited
Hajime Inoue +7 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Comparative Study of Modulation Techniques for Two-Level Voltage Source Inverters
Renewable Energy and Sustainable Development, 2016 A detailed comparative study of modulation techniques for single and three phase dc-ac inverters is presented. Sinusoidal Pulse Width Modulation, Triplen Sinusoidal Pulse Width Modulation, Space Vector Modulation, Selective Harmonic Elimination and ...
Barry W. Williams +3 more
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Powdery mildew infection dependent on weather factors in vineyards near Keszthely in 2008
International Journal of Horticultural Science, 2010 Weather conditions are extremely influential on grapevine productivity and quality. High temperature and humidity makes favorable conditions for powdery mildew infection respectively.
P. Taksony +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
‘Zero energy’ electron beam technology for sludge hygienization
Nukleonika, 2019 Large quantity of sewage sludge originating from wastewater treatment plants is becoming a growing problem from environmental and human health points of view.
Chmielewski Andrzej G., Sudlitz Marcin
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FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
International Journal of Electrical Power & Energy SystemsThe characterization of the competitive interdependence among power consumers in power trading system contributes to pursuing efficient power supply and suppressing peak–valley load differences. Even though Stackelberg–Nash game approach has been applied
Jing Yan +4 more
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FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source