Results 161 to 170 of about 736,237 (386)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

QCD properties of twist operators in the N=6 Chern-Simons theory

open access: yes, 2009
We consider twist-1, 2 operators in planar N=6 superconformal Chern-Simons ABJM theory. We derive higher order anomalous dimensions from integrability and test various QCD-inspired predictions known to hold in N=4 SYM.
A. Agarwal   +32 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

DNA barcoding based on 16S mitochondrial DNA (mtDNA) Molecular Marker of Mangrove Clams from the Selected Sites of Davao Region, Philippines

open access: diamond, 2022
Leonel Lumogdang   +4 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Comparative Mito-Genomic Analysis of Different Species of Genus Canis by Using Different Bioinformatics Tools

open access: yesJournal of Bioresource Management, 2019
In the current study, the mitochondrial genes sequence for COI, Cyt b and 16s rRNA of seven species found in different parts of the world were retrieved from NCBI Gene Bank while, PCR products of COI, Cyt b and 16s rRNA genes obtained from C. lupus and C.
Ume Rumman   +3 more
doaj   +1 more source

Cultivation of \u3cem\u3eTropheryma whipplei\u3c/em\u3e from Cerebrospinal Fluid [PDF]

open access: yes, 2003
Whipple disease (WD) is a systemic disorder caused by the bacterium Tropheryma whipplei. Since the recognition of a bacterial etiology in 1961, many attempts have been made to cultivate this bacterium in vitro.
Fredricks, David N.   +5 more
core   +1 more source

A comparison of random sequence reads versus 16S rDNA sequences for estimating the biodiversity of a metagenomic library [PDF]

open access: gold, 2008
Chaysavanh Manichanh   +5 more
openalex   +1 more source

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