Results 141 to 150 of about 134,692 (313)

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

Advanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi, Zesheng Li, Xin Sun, Yanfeng Yang, Yumin Luo, Ziang Song, Hengxin Dong, Lei Jin, Jing Xie, Yongzhi Shan, Guoguang Zhao   +10 more
wiley   +1 more source

Novel and Efficient Method for Diagnosing Infective Endocarditis Using 16S Ribosomal RNA Gene Amplicon Sequence. [PDF]

JACC Case Rep, 2023
Kataoka A, Shiba T, Katagiri S, Koyama S, Kito K, Ota T, Katayama T, Ohsugi Y, Nagai T, Kobayashi R, Komatsu K, Urata M, Imazuru T, Iwata T, Kozuma K.   +14 more
europepmc   +1 more source

Precursors to 16S and 23S ribosomal RNA from a ribonuclease III⁻strain of Escherichia coli contain intact RNase III processing sites [PDF]

, 1980
Peter Gegenheimer, David Apirion
openalex   +1 more source

The 3'-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites.

Proceedings of the National Academy of Sciences of the United States of America, 1974
J. Shine, L. Dalgarno
semanticscholar   +1 more source

Identifying Tipping Points during Healthy Brain Aging through Single‐Nucleus Transcriptomic Analysis

Advanced Science, EarlyView.
This study applies single‐nucleus transcriptomics and systems dynamics to uncover nonlinear aging patterns in healthy human brains. By introducing dynamic network biomarker theory, the authors identify a critical tipping point at ages 56–60 during aging, and highlight glial instability as a key mediator.
Peiru Wu, Xuyu Zhao, Zixin Chen, Jingying Huang, Tengteng Dai, Jianxin Zhou, Luyao Xiao, Luonan Chen, Robert Chunhua Zhao, Jiao Wang   +9 more
wiley   +1 more source

- Invited Review - Assessment of the gastrointestinal microbiota using 16S ribosomal RNA gene amplicon sequencing in ruminant nutrition. [PDF]

Anim Biosci, 2023
Kim M.
europepmc   +1 more source

Sequence and secondary structure of the colicin fragment of Bacillus stearothermophilus 16S ribosomal RNA [PDF]

, 1981
Rein Van Charldorp, Anita M. A. Van Kimmenade, P.H. Van Knippenberg   +2 more
openalex   +1 more source

Complete nucleotide sequence of a 16S ribosomal RNA gene from Escherichia coli.

Proceedings of the National Academy of Sciences of the United States of America, 1978
J. Brosius, M. L. Palmer, P. J. Kennedy, H. Noller   +3 more
semanticscholar   +1 more source

MicroRNA‐Enriched Plant‐Derived Exosomes Alleviate Colitis by Modulating Systemic Immunity, Metabolic Homeostasis, and Gut Microbiota

Advanced Science, EarlyView.
Herbal medicine, with its multicomponent and multitarget potential, is often studied primarily for traditional forms, especially phytochemicals. Currently, ulcerative colitis lacks natural, low‐toxicity therapies, yet emerging research highlights plant‐derived exosomes as a promising option.
Ruipeng Shi, Wen Tan, Haochun Jin, Sio I Chan, Wei Li, Si San Lei, Guozhen Cui, Yitao Wang, Dong‐Hua Yang, Zhangfeng Zhong   +9 more
wiley   +1 more source

A large scale 16S ribosomal RNA gene amplicon dataset of hand, foot and mouth patients and healthy individuals. [PDF]

Sci Data, 2023
Guo X, Yan M, Huang D, Chen S, Zhang D, Li Z, Yang X, Wu W.   +7 more
europepmc   +1 more source