Results 301 to 310 of about 186,676 (349)

Universal bacterial identification by mass spectrometry of 16S ribosomal RNA cleavage products

, 2006
George W. Jackson, Roger J. McNichols, George E. Fox, Richard C. Willson   +3 more
openalex   +1 more source

Modulation of Gut Microbiota by Protein‐Oligosaccharide Maillard‐Reaction‐Derived Probiotic Microcapsules

Food Bioengineering, EarlyView.
Development of a novel synbiotic microcapsule and its impact on gut microbiota. ABSTRACT As a new type of prebiotic, the Maillard reaction products of protein ‐ oligosaccharide conjugates have emerged as a promising material for probiotic encapsulation and improve host health.
Hongxing Zhang, Yue Shen, Wanting Huang, Xinyi Fang, Yanlin Wang, Xingyuan Ma, Wenyun Zheng   +6 more
wiley   +1 more source

Gordonia species: emerging pathogens in pediatric patients that are identified by 16S ribosomal RNA gene sequencing.

Clinical Infectious Diseases, 2007
A. Blaschke, J. Bender, C. Byington, K. Korgenski, J. Daly, C. Petti, A. Pavia, K. Ampofo   +7 more
semanticscholar   +1 more source

Microbiota‐Dependent Longevity Effects of Aronia Berry (Aronia melanocarpa) in Drosophila melanogaster

Food Frontiers, EarlyView.
Aronia berry extract extends lifespan in Drosophila melanogaster by modulating commensal microbes, reducing oxidative stress, and activating the immune system via the Toll pathway. Its longevity effects are dependent on gut microbiota, highlighting the interplay between polyphenols, microbes, and aging.
Ji‐Hyeon Lee, Hye‐Yeon Lee, Jang‐Cheon Cho, Alexey Moskalev, Kyung‐Jin Min   +4 more
wiley   +1 more source

Postbiotic from Lactobacillus acidophilus Inhibits Ferroptosis in Intestinal Stem Cells via Microbiota–AhR Axis to Mitigate Colitis

Food Frontiers, EarlyView.
Lacidophilin tablets alleviate colitis by regulating gut microbiota balance and maintaining intestinal barrier integrity. ABSTRACT Inflammatory bowel disease (IBD) is a chronic, progressive intestinal disorder. Dysbiosis of the gut microbiota is strongly implicated in the onset and progression of IBD.
Denglong Sun, Chenxuan Wang, Qigui Fan, Yang Zhan, Xiaoying Cheng, Jingwen Zhang, Qinxin Wang, Yingmeng Li, Qiong Li, Yanxia Xiong, Wenjun Liu   +10 more
wiley   +1 more source

Endoplasmic Reticulum Stress Amplifies Cytokine Responses in Astrocytes via a PERK/eIF2α/JAK1 Signaling Axis

Glia, EarlyView.
ER stress amplifies TNF‐α, OSM, and IL‐1β responses in astrocytes. PERK and JAK1 signaling are required for the synergistic interaction between ER stress and inflammatory cytokines. Translational suppression attenuates the synthesis of the negative feedback regulators IκBα and SOCS3.
Anirudhya Lahiri, Savannah G. Sims, Jessica A. Herstine, Alicia Meyer, Micah J. Marshall, Ishrat Jahan, Subhodip Adhicary, Allison M. Bradbury, Gordon P. Meares   +8 more
wiley   +1 more source

Transcriptional Regulation of Microglial Metabolic and Activation States by P2RY12

Glia, EarlyView.
Transcriptionally, P2RY12‐deficient microglia show heightened metabolic activity, iron handling, and oxidative stress at baseline. Upon LPS challenge, impaired glutathione antioxidant responses suggest increased vulnerability to ferroptosis. ABSTRACT Microglia are the resident immune cells of the CNS.
Aida Oryza Lopez‐Ortiz, Madison Doceti, JaQuinta Thomas, Abigayle Duffy, Morgan Coburn, Akhabue K. Okojie, Audrey Lee, Elizabeth Aidita Sou, Alban Gaultier, Ukpong B. Eyo   +9 more
wiley   +1 more source

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

iMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei, Yanhui Lu   +8 more
wiley   +1 more source

Microbiota humanization drives human‐like metabolic and immune transcriptomic shifts in pigs

iMetaOmics, EarlyView.
This study successfully established gut microbiota‐humanized pigs, achieved human‐like remodeling of the serum metabolome, and uncovered transcriptional alterations in immune cell subsets. These findings advance our understanding of how human gastrointestinal microorganisms affect host metabolism and the immune function in a porcine model.
Zhaoqi Zhang, Yanan Xu, Kun Pang, Changhong Wu, Chenxu Zhao, Tong Lei, Jiayu Zhang, Tang Hai, Fangqing Zhao, Yong Zhao   +9 more
wiley   +1 more source