Results 281 to 290 of about 1,073,094 (328)
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Interaction of antibiotics with functional sites in 16S ribosomal RNA
Nature, 1987Chemical footprinting shows that several classes of antibiotics (streptomycin, tetracycline, spectinomycin, edeine, hygromycin and the neomycins) protect concise sets of highly conserved nucleotides in 16S ribosomal RNA when bound to ribosomes. These findings have strong implications for the mechanism of action of these antibiotics and for the ...
Harry F. Noller, Danesh Moazed, D Moazed
exaly +4 more sources
Secondary structure of 16S ribosomal RNA.
Science, 1981A secondary structure model for 16 S ribosomal RNA which is based on available chemical, enzymatic, and comparative sequence data shows good agreement between constraints dictated by the model and a wide variety of experimental observations.
H. Noller, C. Woese
semanticscholar +3 more sources
Scanning tunnelling microscopy of 16S ribosomal RNA in water
Biochemical and Biophysical Research Communications, 1991The scanning tunnelling microscope has been used to image 16S ribosomal RNA molecules in water electrophoretically deposited on graphite surface. Two kinds of images have been obtained: images showing aggregates of 16S ribosomal RNA molecules similar to those obtained from DNA solutions and others showing individual 16S ribosomal RNA molecules.
Eric Lesniewska
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Nuclease S1 mapping of 16S ribosomal RNA in ribosomes
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1990Escherichia coli 16S rRNA and 16S-like rRNAs from other species have several universally conserved sequences which are believed to be single-stranded in ribosomes. The quantitative disposition of these sequences within ribosomes is not known. Here we describe experiments designed to explore the availability of universal 16S rRNA sequences for ...
M A, Rahman, H W, Schaup
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Precursor 16S RNA in Active 30S Ribosomes
Nature, 1974BIOGENESIS of bacterial ribosomes proceeds through the formation of precursor particles1–4, consisting of an incomplete set of ribosomal protein5 and of RNA molecules that are longer and less methylated than mature RNA4,6,7. RNA maturation is commonly considered to be a part of the ribosome maturation process.
MANGIAROTTI, Giorgio +3 more
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Nucleotide Sequences of Sections of 16S Ribosomal RNA
Nature, 1970Three large sections of 16S RNA, obtained by partial enzymatic hydrolysis, and together representing nearly one-fifth of the molecule, have been analysed. Knowledge of their primary structure allows features of the secondary structure to be envisaged.
C, Ehresmann, P, Fellner, J P, Ebel
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Conservation of primary structure in 16S ribosomal RNA
Nature, 1975THERE is no doubt that the large ribosomal RNAs play specific roles in ribosome function1. Yet the thrust of experimentation during the past 5 years indicates clearly that the biologist tends to view these roles as structural, function being reserved by and large for the ribosomal protein components2,3.
C R, Woese +7 more
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Dual-mode Detection of Bacterial 16S Ribosomal RNA in Tissues.
ACS Sensors, 2020The specific detection of pathogens has long been recognized as a vital strategy for controlling bacterial infections. Herein, a novel hydrophilic aromatic-imide-based thermally activated delayed fluorescence (TADF) probe, AI-Cz-Neo, is designed and ...
Shengnan Xu +7 more
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Methylation of 16S RNA during ribosome assembly in vitro
Nature, 1974Methyl deficient 16S RNA from kasugamycin resistant Escherichia coli has been used to study methylation of RNA during ribosome assembly in vitro. Methylation occurs at an intermediate stage and is inhibited at a late stage of assembly. 30S ribosomal proteins required for methylation, and inhibition, have been identified.
P, Thammana, W A, Held
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