Results 61 to 70 of about 1,073,094 (328)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Molecular and Morphological identification of the genus Dineutus MacLeay, 1825 (Coleoptera, Gyrinidae) from Eastern Ghats, India [PDF]

Journal of Insect Biodiversity and Systematics, 2023
The present study is on the morphology and molecular data of the genus Dineutus MacLeay, were collected from the Eastern Ghats mountains in Odisha, Andhra Pradesh, Telangana, Tamil Nadu states located in the eastern Ghats of India.
Jaiswal Deepa, Shiva Shankar, Devadoss Kumar, Karuthapandi Madasamy, Shrikant Jadhav, Rehanuma Sulthana   +5 more
doaj  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

First report on molecular characterization of Streptococcus pluranimalium from Sirohi goat

Indian Journal of Animal Sciences
The present study was done with an objective to identify the causative agent(s) involved in the causation of cutaneous abscessation in goat from semi-arid region of Rajasthan, India by using conventional bacteriological and PCR protocols targeting 16S ...
G NAGARAJAN, GHANSHYAM YADAV, RAJIV KUMAR, D K SHARMA, A S MEENA, G G SONAWANE, S S MISRA, ARUN KUMAR   +7 more
doaj   +1 more source

Diagnostic Techniques for Early Detection of Phytoplasma Diseases

Syrian Journal for Science and Innovation, 2023
Phytoplasmas are a type of bacteria, specifically belonging to the group of Mollicutes, characterized by their lack of cell walls and inability to be cultured in lab settings.
Naofel Aljafer, Hail Rihan
doaj   +1 more source

Molecular biological methods for studying the gut microbiota : the EU human gut flora project [PDF]

, 2002
Seven European laboratories co-operated in a joint project (FAIR CT97-3035) to develop, refine and apply molecular methods towards facilitating elucidation of the complex composition of the human intestinal microflora and to devise robust methodologies ...
Vos, W.M., de, Collins, M.D., Welling, G.W., Loo, J., van, Blaut, M., Dore, J.   +5 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Primary sequence of the 16S ribosomal RNA of Escherichia coli

Nucleic Acids Research, 1975
Recent progress in the nucleotide sequence analysis of the 16S ribosomal RNA from E. coli is described. The sequence which has been partially or completely determined so far encompasses 1520 nucleotides, i.e. about 95% of the molecule. Possible features of the secondary structure are suggested on the basis of the nucleotide sequence and data on ...
C, Ehresmann, P, Stiegler, G A, Mackie, R A, Zimmermann, J P, Ebel, P, Fellner   +5 more
openaire   +3 more sources

Nop53p is required for late 60S ribosome subunit maturation and nuclear export in yeast [PDF]

, 2005
We report that Ypl146cp/Nop53p is associated with pre-60S ribosomal complexes and localized to the nucleolus and nucleoplasm. in cells depleted of Nop53p synthesis of the rRNA components of the 60S ribosomal subunit is severely inhibited, with strikingly
Tollervey, D, Thomson, E
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source