Advanced Science, EarlyView.This study presents an engineered human interferon‐lambda (hIFN‐λ) as an intranasal prophylactic against respiratory viruses. By combining AI‐guided backbone redesign and glycoengineering, the authors developed a thermostable, protease‐resistant, and scalable variant with improved mucosal penetration.
Jeongwon Yun +12 more
wiley +1 more source
Identification of Host-Specific Bacteroidales 16S rDNA Sequences from Human Sewage and Ruminant Feces [PDF]
, 2011 The need to identify the source of fecal contamination of water has led to the development of various fecal source identification methods, a field known as microbial source tracking (MST). One promising method of MST focuses on fecal members of the order
Allsop +25 more
core +1 more source
Advanced Science, EarlyView.The chimeric RNA ERCC1‐iASPP possesses dual coding and non‐coding functions, synergistically accelerating the process of cellular malignant transformation. Abstract Genetic variation at 19q13.3 critically modulates chemical carcinogen‐induced lung carcinogenesis, particularly in mediating the activity of benzo[a]pyrene (B[a]P), a major polycyclic ...
Mingming Shan +9 more
wiley +1 more source
Enumeration, identification and characterisation of methanogens colonising pre-ruminant calves : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science at Massey University, Palmerston North, New Zealand [PDF]
, 2007 Methane-producing archaea, methanogens, in ruminant animals are a major source of anthropogenic methane. With a global warming potential 23 times greater than carbon dioxide, methane has been targeted for reduction under the Kyoto protocol.
Evans, Paul Nicolas
core
Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier
Advanced Science, EarlyView.SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao +11 more
wiley +1 more source
Identification of Indigenous Bacteria from Dumai Sea Waters Using 16S rRNA Method
, 2021 Esa Buana Fatwa +2 more
openalex +2 more sources
Neisseria oralis sp. nov., isolated from healthy gingival plaque and clinical samples [PDF]
, 2013 A polyphasic analysis was undertaken of seven independent isolates of Gram-negative cocci collected from pathological clinical samples from New York, Louisiana, Florida and Illinois and healthy subgingival plaque from a patient in Virginia, USA.
Carpenter, Andrea N. +13 more
core +1 more source
Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen
Advanced Science, EarlyView.Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang +12 more
wiley +1 more source
DIAGNOSIS OF BACTEREMIA USING UNIVERSAL PCR IN FEBRILE ILL CHILDREN [PDF]
Acta Medica Iranica, 2007 Early diagnosis of bacteremia and its complications is the most important part of care and management of the febrile patients. However, a majority of patients who appear to be clinically septic have negative blood culture.
Afsharpaiman +4 more
doaj +1 more source