Results 121 to 130 of about 417,138 (346)
Taxonomy annotation and guide tree errors in 16S rRNA databases
PeerJ, 2018 Sequencing of the 16S ribosomal RNA (rRNA) gene is widely used to survey microbial communities. Specialized 16S rRNA databases have been developed to support this approach including Greengenes, RDP and SILVA.
Robert C. Edgar
semanticscholar +1 more source
Advanced Science, EarlyView.Vascular smooth muscle cells (VSMCs)‐specific deficiency of PP2Acα exacerbates aortic aneurysm and dissection (AAD) by promoting phenotypic switching through AKT1‐mediated phosphorylation and stabilization of Kruppel‐like factor 4 (KLF4). Reduced PP2Acα enhances KLF4 ubiquitination resistance, suppressing VSMC contractile genes and accelerating aortic ...
Wei‐Peng Hu +7 more
wiley +1 more source
Organization of the Proteostasis Network of Membraneless Organelles
Advanced Science, EarlyView.A comprehensive mapping of the proteostasis network (PN) across membraneless organelles (MLOs) reveals how central PN components coordinate MLO regulation. The analysis uncovers principles of specificity and promiscuity within the PN. The findings suggest that HSP70 chaperones act as generic MLO regulators, while client specific HSP70 co‐chaperones may
Christine M. Lim +6 more
wiley +1 more source
Polyphyly in 16S rRNA-based LVTree Versus Monophyly in Whole-genome-based CVTree
Genomics, Proteomics & Bioinformatics, 2018 We report an important but long-overlooked manifestation of low-resolution power of 16S rRNA sequence analysis at the species level, namely, in 16S rRNA-based phylogenetic trees polyphyletic placements of closely-related species are abundant compared to ...
Guanghong Zuo, Ji Qi, Bailin Hao
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Mutation analysis of 16S rRNA in patients with Rett syndrome
Pediatric Neurology, 2000 Rett syndrome (RTT) is a progressive neurodevelopmental disorder that affects one in 10,000-15,000 females. RTT is mainly sporadic; familial cases have an estimated frequency of less than 1%. Before the recent identification of de novo dominant mutations in the X-linked MECP2 gene, many other hypotheses had been proposed to explain the particular ...
Mercè Pineda +2 more
openaire +4 more sources
Advanced Science, EarlyView.Wound infections induce gcFGF8a expression, which subsequently executes direct antimicrobial activity to suppress local infection while simultaneously activating the FGFR4‐mediated ERK/AKT‐mTOR signaling cascade, thereby upregulating HIF1α and enhancing glycolysis. These coordinated actions synergistically promote tissue repair by eliminating pathogens
Ya‐Zhen Hu +6 more
wiley +1 more source
Novel arrangement of rRNA genes in Mycoplasma gallisepticum: separation of the 16S gene of one set from the 23S and 5S genes [PDF]
, 1989 Xuemin Chen, Lloyd R. Finch
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Advanced Science, EarlyView.Drought is a major cause of crop losses across agricultural regions. Rhizosheath formation enhances plant resistance to drought. Polyploids may tolerate stress more effectively through increased interactions with bacteria. However, the contributions of tetraploid rice associated microbiota to rhizosheath formation under soil drying remain unclear ...
Feiyun Xu +23 more
wiley +1 more source
浙江大学学报. 农业与生命科学版, 2015 Thermophilic bacterium, strain CHBT-1721 is the first thermophilic microorganism isolated from the hot spring of Bantang in Chaohu of Anhui Province and the phylogenetic relationship of this strain with other thermophile bacteria isolated from hot ...
Fang Shu, Dai Chong, Yan Juan
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Controlling for Contaminants in Low-Biomass 16S rRNA Gene Sequencing Experiments
mSystems, 2018 The relative scarcity of microbes in low-microbial-biomass environments makes accurate determination of community composition challenging. Identifying and controlling for contaminant bacterial DNA are critical steps in understanding microbial communities
Lisa Karstens +7 more
semanticscholar +1 more source