Results 81 to 90 of about 109,607,141 (279)

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Processing map of 17-4 PH martensitic stainless steel and microstructural evolution during hot deformation

Journal of Materials Research and Technology
The experimental material utilised was a low-carbon 17-4 PH martensitic stainless steel (MSS), and single-axis hot compression tests were executed at diverse deformation temperatures (950–1200 °C) and strain rates (0.001–10 s−1) employing a Gleeble 3800 ...
Huiling Zhou, Ruimin Gao, Shugang Zhang, Chengtao Li, Xin Yao, Mingyue Sun, Sheng Lu, Yanxin Qiao   +7 more
doaj   +1 more source

Bio-materials for intramedullary pin application in canine femur: a comparative analysis [PDF]

Exploration of BioMat-X
Aim: In this study, the finite elements analysis (FEA) was performed on an intramedullary (IM) pin to be used in the canine femur. The 03 different biomaterials [17-4-precipitated hardened (PH)-stainless steel (SS), nickel alloys (Ni)-625, titanium ...
Minhaz Husain, Rupinder Singh, Bahadur Singh Pabla, Gurwinder Singh, J. P. Davim   +4 more
doaj   +1 more source

Toplotne lastnosti jekla 17-4 ph

, 2020
The diploma thesis describes the process of measuring thermal properties of stainless steel 17 4 ph (W.nr. 1.4542) with the transient planar source method (Hot disk ®). All measurements were performed in accordance with the ISO 22007-2 standard. Thermal properties such as: thermal conductivity, thermal diffusivity and specific heat were considered and ...
openaire   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Performance of miniaturised thick-film solid state pH sensors [PDF]

, 2012
The performance of novel solid-state Thick-Film pH sensor for water quality sampling suitable for deployment in remote catchment areas is described. These miniaturised screen printed planar pH sensors are an alternative to glass pH electrodes, which have
Atkinson, John, Glanc-Gostkiewicz, M., Atkinson, J.K., Sophocleous, Marios, Garcia-Breijo, Eduardo, Sophocleous, M., Glanc, M., Atkinson, John Karl, Glanc-Gostkiewicz, Monika, Garcia Breijo, Eduardo   +9 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source