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A Delayed Presentation of Salt-Wasting Congenital Adrenal Hyperplasia Due to 3β-Hydroxysteroid Dehydrogenase Deficiency in an Infant: A Case Report. [PDF]
CureusGhareeb BM +3 more
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Prevention of Recurrent Preterm Delivery by 17 Alpha-Hydroxyprogesterone Caproate
New England Journal of Medicine, 2003Women who have had a spontaneous preterm delivery are at greatly increased risk for preterm delivery in subsequent pregnancies. The results of several small trials have suggested that 17 alpha-hydroxyprogesterone caproate (17P) may reduce the risk of preterm delivery.We conducted a double-blind, placebo-controlled trial involving pregnant women with a ...
Jay Iams, Michael W. Varner, Baha Sibai
exaly +8 more sources
A Trial of 17 Alpha-Hydroxyprogesterone Caproate to Prevent Prematurity in Twins
New England Journal of Medicine, 2007In singleton gestations, 17 alpha-hydroxyprogesterone caproate (17P) has been shown to reduce the rate of recurrent preterm birth. This study was undertaken to evaluate whether 17P would reduce the rate of preterm birth in twin gestations.We performed a randomized, double-blind, placebo-controlled trial in 14 centers. Healthy women with twin gestations
Jay Iams +2 more
exaly +3 more sources
Medical Cost Savings Associated With 17 Alpha-Hydroxyprogesterone Caproate
American Journal of Obstetrics and Gynecology, 2007This study was undertaken to assess the impact of 17 alpha hydroxyprogesterone caproate treatment on future medical costs for expectant mothers with a prior spontaneous preterm birth.Data on the costs of preterm birth were combined with published data on the effectiveness of 17 alpha hydroxyprogesterone caproate to produce estimates of the effect of ...
Jennifer L Bailit
exaly +3 more sources
Progesterone, but Not 17-Alpha-Hydroxyprogesterone Caproate, Inhibits Human Myometrial Contractions
American Journal of Obstetrics and Gynecology, 2008The aim was to determine whether progesterone (P4) or 17-alpha-hydroxyprogesterone caproate (17P) directly inhibit human uterine contractility in vitro and thereby clarify their mechanisms of action.Myometrial tissues were suspended in organ chambers and exposed for 2 to 20 hours to varying concentrations of P4 or 17P or solvent.
Roberto Romero +2 more
exaly +3 more sources
Effect of Endogenous Steroid Hormones on 17-Alpha-Hydroxyprogesterone Caproate Metabolism
American Journal of Obstetrics and Gynecology, 2013Plasma concentrations of 17-alpha-hydroxyprogesterone caproate (17-OHPC) vary substantially in pregnant patients who receive an identical dose. Endogenous steroid hormones may alter 17-OHPC metabolism, which contributes to this large variability.Pooled human liver microsomes were incubated with 17-OHPC alone or in combination with progesterone ...
Wenchen Zhao +2 more
exaly +3 more sources
17 Alpha-hydroxyprogesterone caproate use in a rural state
The Journal of Maternal-Fetal & Neonatal Medicine, 202117 alpha-hydroxyprogesterone caproate (17OHP) is used to reduce the recurrent risk of preterm delivery in women with a history of preterm delivery. Meis et al. conducted a double-blind placebo controlled trial to evaluate the effectiveness of 17OHP and observed a significant reduction in the risk of recurrent preterm delivery.
Taylor Ghahremani +6 more
openaire +2 more sources