Results 1 to 10 of about 11,654 (206)

Gender-Specific Independent and Combined Effects of the Progesterone and 17-Hydroxyprogesterone on Metabolic Syndrome: From the Henan Rural Cohort Study [PDF]

Diabetes, Metabolic Syndrome and Obesity, 2021
Mian Wang,1,* Luting Nie,1,* Dandan Wei,2 Pengling Liu,2 Li Zhang,2 Keliang Fan,2 Yu Song,1 Lulu Wang,2 Qingqing Xu,2 Juan Wang,2 Xiaotian Liu,2 Linlin Li,2 Zhenxing Mao,2 Chongjian Wang,2 Wenqian Huo1 1Department of Occupational and ...
Wang M, Nie L, Wei D, Liu P, Zhang L, Fan K, Song Y, Wang L, Xu Q, Wang J, Liu X, Li L, Mao Z, Wang C, Huo W   +14 more
doaj   +2 more sources

First Morning Pregnanetriol and 17-Hydroxyprogesterone Correlated Significantly in 21-Hydroxylase Deficiency [PDF]

Frontiers in Endocrinology, 2022
BackgroundBiochemically monitoring 21-hydroxylase deficiency (21-OHD) is challenging. Serum/blood 17-hydroxyprogesterone (17OHP) measurements are normally used for this purpose. Urinary pregnanetriol (PT), a urinary metabolite of 17OHP, may also be used.
Tomoyo Itonaga, Tomoyo Itonaga, Masako Izawa, Takashi Hamajima, Yukihiro Hasegawa   +4 more
doaj   +2 more sources

An unusual cause of adrenal insufficiency with elevation of 17-hydroxyprogesterone: case report [PDF]

BMC Endocrine Disorders, 2023
Background We present an intriguing case of primary adrenal lymphoma, with associated primary adrenal insufficiency (PAI), in a patient presenting a transitory partial 21-hydroxylase deficiency during the active phase of the adrenal disease.
Claudia Teti, Giampaolo Bezante, Federico Gatto, Keyvan Khorrami Chokami, Manuela Albertelli, Marco Falchi, Giulio Bovio, Sandro Teresio Nati, Diego Ferone, Mara Boschetti   +9 more
doaj   +2 more sources

Adrenal adenoma secreting 17-hydroxyprogesterone mimicking non-classical 21-hydroxylase deficiency [PDF]

Frontiers in Endocrinology
In adrenal steroidogenesis, 17-hydroxyprogesterone (17-OHP) is a substrate for 21-hydroxylase, one of the crucial enzymes of the cortisol and aldosterone biosynthesis pathway.
Beata Woźniak, Dorota Leszczyńska, Alicja Szatko, Alicja Szatko, Karolina Nowak, Radosław Samsel, Anna Siejka, Lucyna Papierska, Wojciech Zgliczyński, Henrik Falhammar, Henrik Falhammar, Piotr Glinicki, Piotr Glinicki   +12 more
doaj   +2 more sources

Pharmacokinetics of 17-hydroxyprogesterone caproate in multifetal gestation

American Journal of Obstetrics and Gynecology, 2011
To define the pharmacokinetic (PK) parameters of 17-hydroxyprogesterone caproate (17-OHPC) in multifetal gestation.
Steve N Caritis, Raman Venkataramanan, Dwight J Rouse   +2 more
exaly   +4 more sources

Can 17 hydroxyprogesterone caproate (17P) decrease preterm deliveries in patients with a history of PMC or pPROM? [PDF]

PLoS ONE, 2022
Background A history of spontaneous preterm birth (sPTB) is a significant risk factor for recurrence. Intra-muscular-7α-hydroxyprogesterone caproate (17P) has been the preventive treatment of choice until the recent “Prolong study” that reported no ...
Gal Cohen, Maya Shavit, Netanella Miller, Rimon Moran, Yael Yagur, Omer Weitzner, Michal Ovadia, Hanoch Schreiber, Gil Shechter-Maor, Tal Biron-Shental   +9 more
doaj   +2 more sources

Individual 17-Hydroxyprogesterone Responses to hCG Are Not Correlated With Follicle Size in Polycystic Ovary Syndrome. [PDF]

J Endocr Soc, 2019
Context:In women with polycystic ovary syndrome (PCOS), 17-hydroxyprogesterone (17-OHP) responses to gonadotropin stimulation vary from increased to indistinguishable compared with normal controls.
Homer MV, Toloubeydokhti T, Lawson MA, Garzo G, Duleba AJ, Chang RJ.   +5 more
europepmc   +4 more sources

Quality assessment of compounded 17-hydroxyprogesterone caproate. [PDF]

Am J Obstet Gynecol, 2014
The purpose of this study was to evaluate the quality of compounded 17-hydroxyprogesterone caproate (17-OHPC).Compounded 17-OHPC that was obtained from 15 compounding pharmacies throughout the United States was analyzed for potency, impurities, sterility, and pyrogen status.Eighteen samples were supplied by 15 compounding pharmacies.
Chang J, Zhao Y, Zhao W, Venkataramanan R, Caritis SN, Obstetrical-Fetal Pharmacology Research Units Network.   +5 more
europepmc   +4 more sources

Measurement of 17-Hydroxyprogesterone by LCMSMS Improves Newborn Screening for CAH Due to 21-Hydroxylase Deficiency in New Zealand [PDF]

International Journal of Neonatal Screening, 2020
The positive predictive value of newborn screening for congenital adrenal hyperplasia due to 21-hydroxylase deficiency was <2% in New Zealand. This is despite a bloodspot second-tier immunoassay method for 17-hydroxyprogesterone measurement with an ...
Mark R de Hora, Natasha L Heather, Tejal Patel, Lauren G Bresnahan, Dianne Webster, Paul L Hofman   +5 more
doaj   +2 more sources

Prevention of preterm delivery with 17-hydroxyprogesterone caproate: pharmacologic considerations. [PDF]

Semin Perinatol, 2014
Despite advances in neonatal care, the burden of preterm birth remains high. Preterm birth is a multifactorial problem, and strategies to identify and treat medical risk factors in early pregnancy have not been effective in reducing preterm birth rates.
Feghali M, Venkataramanan R, Caritis S.
europepmc   +4 more sources