The importance of elevated basal 17-hydroxyprogesterone in the diagnosis of children with congenital adrenal hyperplasia [PDF]
Background: Congenital adrenal hyperplasia (CAH) is usually characterised by a deficiency of 21a-hydroxylase, which causes a deficiency of cortisol and aldosterone and an overproduction of 17-hydroxyprogesterone.
Miolski Jelena +10 more
doaj +1 more source
Background: Preterm birth (PTB) is a pressing maternal and child health issue with long-standing racial inequities in outcomes and care provision. 17-Alpha-hydroxyprogesterone caproate (17OHPC) has been one of few clinical interventions for recurrent PTB
Stephanie M. Garcia +4 more
doaj +1 more source
Effect of 17 α-Hydroxyprogesterone Caproate on the Prevention of Preterm Labor: A Randomized Controlled Trial Study [PDF]
Background & aim: Based on the previous reports, treatment with 17 α-Hydroxyprogesterone caproate (17-OHPC) decreased the risk of preterm labor (PTL). However, some studies indicated contrasting results.
Hamed Jafarpour +4 more
doaj +1 more source
Growth Patterns in the First Three Years of Life in Children with Classical Congenital Adrenal Hyperplasia Diagnosed by Newborn Screening and Treated with Low Doses of Hydrocortisone [PDF]
Background: Linear growth is the best clinical parameter for monitoring metabolic control in classical congenital adrenal hyperplasia (CAH). Objective: To analyze growth patterns in children with CAH diagnosed by newborn screening and treated with ...
Bonfig, W., Schmidt, H., Schwarz, H. P.
core +1 more source
Effects of inhalation of oil-paint fumes of construction industry on serum level of FSH, LH, estradiol and 17-alpha- hydroxyprogesterone in female rats [PDF]
Background & Objective: Studies have shown that exposure to oil paint and chemical vapor emissions is followed by physiological disorders. The aim of this study was to determine the effects of inhalation of oil-paint fumes of construction industry on ...
Maryam Siavashi +2 more
doaj +2 more sources
17-Hydroxyprogesterone caproate to prolong pregnancy after preterm rupture of the membranes: early termination of a double-blind, randomized clinical trial [PDF]
Background Progestational agents may reduce the risk of preterm birth in women with various risk factors. We sought to test the hypothesis that a weekly dose of 17-hydroxyprogesterone caproate (17P) given to women with preterm rupture of the membranes ...
C Andrew Combs +8 more
core +2 more sources
Adrenocortical carcinoma in a 6-month-old infant
Adrenocortical carcinoma (ACC) is a rare malignant tumor arising from the adrenal cortex and it is even rarer in infancy. These tumors are usually hormonally active.
Seema Rahar +5 more
doaj +1 more source
Initial Metabolic Profiles Are Associated with 7-Day Survival among Infants Born at 22-25 Weeks of Gestation. [PDF]
OBJECTIVE:To evaluate the association between early metabolic profiles combined with infant characteristics and survival past 7 days of age in infants born at 22-25 weeks of gestation. STUDY DESIGN:This nested case-control consisted of 465 singleton live
Anderson, James G +9 more
core +1 more source
Over the last 10 years, trilostane, a competitive inhibitor of steroid synthesis, is being widely used for the treatment of canine hyperadrenocorticism.
Alenza +59 more
core +1 more source
Limitations of 17-hydroxyprogesterone in investigating neonatal hyponatraemia [PDF]
Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency is a possible cause of hyponatraemia in the neonate. Elevated 17-hydroxyprogesterone (17-OHP) is considered diagnostic of the condition, although there have been reports of anomalous high concentrations, up to 110 nmol/L, in premature, sick infants subsequently shown to have normal ...
Adel A A, Ismail +3 more
openaire +2 more sources

