Results 91 to 100 of about 140,614 (262)

Transformer‐Based PET/CT Fusion Enables Preoperative Prediction and Prognostic Stratification of Spread Through Air Spaces in Lung Adenocarcinoma

Advanced Science, EarlyView.
An eight‐stream 2.5D Transformer integrates complementary PET metabolic and CT morphologic information to estimate spread‐through‐air‐spaces risk before surgery in lung adenocarcinoma. The model generalizes across independent centers, while its continuous risk score independently stratifies progression‐free survival, supporting further prospective ...
Xin‐Yu Zhu, Meng Meng, Zhen‐Zhen Wang, Deng‐Lu Lu, Ya‐Min Wei, Xu‐Chang Mi, Xing‐Yu Mu, Wei Fu   +7 more
wiley   +1 more source

Molecular Rectification: Mechanisms, Modulation Strategies, and Device Realization

Advanced Science, EarlyView.
This review focuses on molecular rectification, from its fundamental mechanisms and modulation strategies to device realization. It summarizes the theoretical framework, modulation strategies, fabrication techniques, characterization methods, and modeling and simulation of molecular rectifiers, while discussing challenges and future directions for ...
Junnan Guo, Shufan Song, Wenhui Fang, Jifeng Tang, Wenhao Li, Weikang Wu, Shishen Yan, Hui Li, Lishu Zhang   +8 more
wiley   +1 more source

Radiosynthesis of 18F-labeled reagents for the 18F-difluoromethylation of heteroarenes [PDF]

, 2020
The reagent difluoromethyl benzothiazolyl-sulfone (1) has been extensively used in the difluoromethylation of substrates bearing C=C, C≡C, and C≡N bonds by visible light photoredox catalysis. Taking advantage of the reactivity of 1 as difluoromethylating
Lemos, Agostinho
core   +1 more source

Magnetic Thermal Ablation Combined with Temporally Coordinated CpG Immunotherapy Promotes cDC1‐Dependent Immune Priming in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Novel PLA@Fe3O4 magnetic microspheres were developed for transarterial magnetic hyperthermia ablation (MTA) of hepatocellular carcinoma. While destroying local tumors and inducing immunogenic cell death (ICD), MTA combined with early CpG adjuvant administration significantly promotes cDC1‐dependent immune priming. This synergistic mechanism effectively
Jiakun Yang, Nailin Yang, Shuangshuang Ji, Siping Meng, Di Wang, Wenjun Liang, Xuming Bai, Yong Jin, Xingwei Sun   +8 more
wiley   +1 more source

A novel 18F-labelled tetrazine ester prosthetic group for improved radiolabelling and in vivo stability of proteins and peptides

EJNMMI Radiopharmacy and Chemistry
Background Monoclonal antibodies, engineered protein scaffolds, and peptides are increasingly important in therapy and diagnostics owing to their high specificity and affinity.
Francesco Lechi, Luke R. Odell, Olivia Wegrzyniak, Lorenzo J. I. Balestri, Olof Eriksson, Jonas Eriksson   +5 more
doaj   +1 more source

Deciphering Intricacies in Directional CO2 Conversion From Electrolysis to CO2 Batteries

Advanced Energy Materials, EarlyView.
This review will delve into the inherent connections and distinctions of CO2‐directed conversion in ECO2RR and CO2 batteries, in terms of product types, catalyst selection, catalytic mechanisms, and electrochemical performances, while proposing a benchmarking framework for the evaluation of CO2 batteries and innovative CO2 battery configurations for ...
Changfan Xu, Huaping Zhao, Lizhuang Chen, Weidong Shi, Guosheng Shao, Yong Lei   +5 more
wiley   +1 more source

Preliminary Biological Evaluation of 18F-FBEM-Cys-Annexin V a Novel Apoptosis Imaging Agent

Molecules, 2015
A novel annexin V derivative (Cys-Annexin V) with a single cysteine residue at its C-terminal has been developed and successfully labeled site-specifically with 18F-FBEM.
Chunxiong Lu, Quanfu Jiang, Minjin Hu, Cheng Tan, Huixin Yu, Zichun Hua   +5 more
doaj   +1 more source

Siirtymämetallien käyttö 18F-fluorireaktioissa [PDF]

, 2019
Fluori-18 on hyvin suosittu nuklidi PET-kuvantamisessa ja yhä useampi merkkiaine halutaan leimata sillä. Kaikkia molekyylejä ei kuitenkaan pystytä 18F-fluoraamaan perinteisillä menetelmillä tai niiden radiokemialliset saannot ovat olleet huonoja ...
Rajala, Noora
core  

Current Status and Challenges of Imaging‐Based Diagnosis of Lymph Node Metastasis in Colon Cancer: The Lymph Node Committee of the Japanese Society for Cancer of the Colon and Rectum

Annals of Gastroenterological Surgery, EarlyView.
This review of the status and challenges of diagnosis of lymph node metastasis in colon cancer suggests that it is currently difficult to establish strict criteria for lymph node metastasis, indicating only moderate diagnostic performance. ABSTRACT Background Accurate pre‐treatment evaluation of lymph node metastasis (LNM) in colon cancer is important ...
Shimpei Ogawa, Yuji Takayama, Yasuyuki Takamizawa, Yukihide Kanemitsu, Hideki Ueno   +4 more
wiley   +1 more source

Development of a halofluorocarbon, chromatography-free radiosynthesis of fluorine-18 difluorocarbene

EJNMMI Radiopharmacy and Chemistry
Background In recent years, the development of the [18F]difluoromethyl radical ([18F]2-((difluoromethyl)sulfonyl)benzo[d]thiazole, [18F]4), and [18F]difluorocarbene ([18F]1-chloro-4-((difluoromethyl)sulfonyl)benzene, [18F]10) prosthetic groups, has paved
Catherine G. F. Dickmann, Andrew D. Bond, Selena Milicevic Sephton, Franklin I. Aigbirhio   +3 more
doaj   +1 more source