Optimal eukaryotic 18S and universal 16S/18S ribosomal RNA primers and their application in a study of symbiosis. [PDF]
PLoS ONE, 2014 Eukaryotic 18S ribosomal RNA (rRNA) gene primers that feature a wide coverage are critical in detecting the composition of eukaryotic microscopic organisms in ecosystems.
Yong Wang +4 more
doaj +3 more sources
Structural and functional analysis of Utp24, an endonuclease for processing 18S ribosomal RNA. [PDF]
PLoS ONE, 2018 The precursor ribosomal RNA is processed by multiple steps of nucleolytic cleavage to generate mature rRNAs. Utp24 is a PIN domain endonuclease in the early 90S precursor of small ribosomal subunit and is proposed to cleave at sites A1 and A2 of pre-rRNA.
Weidong An, Yifei Du, Keqiong Ye
doaj +4 more sources
The 18S ribosomal RNA m6 A methyltransferase Mettl5 is required for normal walking behavior in Drosophila. [PDF]
EMBO Rep, 2020 RNA modifications have recently emerged as an important layer of gene regulation. N6‐methyladenosine (m6A) is the most prominent modification on eukaryotic messenger RNA and has also been found on noncoding RNA, including ribosomal and small nuclear RNA.
Leismann J +11 more
europepmc +2 more sources
PEMA: a flexible Pipeline for Environmental DNA Metabarcoding Analysis of the 16S/18S ribosomal RNA, ITS, and COI marker genes. [PDF]
Gigascience, 2020 Background Environmental DNA and metabarcoding allow the identification of a mixture of species and launch a new era in bio- and eco-assessment. Many steps are required to obtain taxonomically assigned matrices from raw data.
Zafeiropoulos H +7 more
europepmc +2 more sources
Exonuclease resistant 18S and 25S ribosomal RNA components in yeast are possibly newly transcribed by RNA polymerase II [PDF]
BMC Molecular and Cell Biology, 2020 Background We have previously reported 18S and 25S ribosomal RNA molecules in Candida albicans resistant to processive 5′ → 3′ exonuclease, appearing as cells approached stationary growth phase. Initial analysis pointed to extra phosphate(s) at their 5′-
Jacob Fleischmann +4 more
doaj +2 more sources
18S Ribosomal RNA Evaluation as Preanalytical Quality Control for Animal DNA. [PDF]
Biomed Res Int, 2016 The 18S ribosomal RNA (rRNA) gene is present in all eukaryotic cells. In this study, we evaluated the use of this gene to verify the presence of PCR-amplifiable host (animal) DNA as an indicator of sufficient sample quality for quantitative real-time PCR
Leonard CA, Meli ML, Novacco M, Borel N.
europepmc +2 more sources
Site-specific methylation of 18S ribosomal RNA by SNORD42A is required for Acute Myeloid Leukemia cell proliferation. [PDF]
Blood, 2020 Non-coding RNAs including small nucleolar RNAs (snoRNAs) play important roles in leukemogenesis but the relevant mechanisms remain incompletely understood.
C. Pauli +13 more
semanticscholar +2 more sources
Methyltransferase ATMETTL5 writes m6A on 18S ribosomal RNA to regulate translation in Arabidopsis. [PDF]
New PhytologistAberrant RNA modifications can lead to dysregulated gene expression and impeded growth in plants. Ribosomal RNA (rRNA) constitutes a substantial portion of total RNA, while the precise functions and molecular mechanisms underlying rRNA modifications in ...
Peizhe Song +8 more
semanticscholar +2 more sources
Atypical U3 snoRNA Suppresses the Process of Pterygium Through Modulating 18S Ribosomal RNA Synthesis. [PDF]
Invest Ophthalmol Vis Sci, 2022 Zhang X +6 more
europepmc +2 more sources
Effects of In Utero EtOH Exposure on 18S Ribosomal RNA Processing: Contribution to Fetal Alcohol Spectrum Disorder. [PDF]
Int J Mol Sci, 2023 Darbinian N +8 more
europepmc +3 more sources