Results 131 to 140 of about 587,426 (318)
Advanced Science, EarlyView.RNA modification is crucial in fibrosis diseases, but the role of m1A modification remains elusive. This study reveals that ALKBH3, an m1A demethylase, drives skin fibrosis by reshaping m6A RNA modification and stabilizing COL1A1 and FN1 mRNAs through METTL3, uncovering a crosstalk between m1A and m6A methylation in pathological events.
Liying Tu +9 more
wiley +1 more source
Small subunit (18S) ribosomal RNA gene divergence in the genus Schistosoma
Parasitology, 1993 SUMMARYAn entire 18S rRNA gene sequence from Schistosoma spindale (1990 bases) and partial 18S rRNA gene sequences from S. haematobium (1950 bases) and S. japonicum (1648 bases) have been determined. Together with the previously published sequence for the S.
Johnston, D A, Kane, R A, Rollinson, D
openaire +3 more sources
Developmental Dynamics, Volume 251, Issue 12, Page 1968-1981, December 2022., 2022 Abstract Background Injury response is key to successful regeneration. Yet, transcriptome analyses of injury response were performed only on a handful of regenerative organisms. Here, we studied the injury response of the solitary ascidian Polycarpa mytiligera, an emerging model system, capable of regenerating any body part.
Noam Hendin +3 more
wiley +1 more source
Optical Probes for Cellular Imaging of G‐quadruplexes: Beyond Fluorescence Intensity Probes
Angewandte Chemie, EarlyView.DNA and RNA can fold into tetra‐stranded helical structures known as G‐quadruplexes (G4s). There is mounting evidence suggesting that these structures have important biological roles. In this minireview we discuss advances in the design of optical probes for the detection of G4s that offer intensity‐independent readouts that address limitations of ...
Jenna Robinson +3 more
wiley +2 more sources
Advanced Science, EarlyView.The gut microbiome is a potential target for treating cardiovascular disease. It is found that prophylactic administration of Flavonifractor plautii or its metabolite desaminotyrosine (DAT) exerts pleiotropic cardioprotective effects via promoting cardiomyocyte survival and attenuating cardiac inflammation against myocardial ischemia/reperfusion (I/R ...
Heng Du +21 more
wiley +1 more source
ELECTROPHORESIS, Volume 43, Issue 23-24, Page 2402-2427, December 2022., 2022 Abstract Nucleic acids are the blueprint of life. They are not only the construction plan of the single cell or higher associations of them, but also necessary for function, communication and regulation. Due to the pandemic, the attention shifted in particular to their therapeutic potential as a vaccine. As pharmaceutical oligonucleotides are unique in
Robert Minkner +3 more
wiley +1 more source
U17XS8, a small nucleolar RNA with a 12 nt complementarity to 18S rRNA and coded by a sequence repeated in the six introns ofXenopus laevisribosomal protein S8 gene [PDF]
, 1994 Francesco Cecconi +5 more
openalex +1 more source
Advanced Science, EarlyView.A CO‐releasing polyoxometalates nanozyme (PMC) is engineered by coordinating pentacarbonyl manganese bromide with molybdenum‐based polyoxometalates nanoclusters. PMC exhibits targeted accumulation at IBD sites, efficient ROS scavenging, and responsive CO release.
Hongyang Lu +16 more
wiley +1 more source
Engineering in Life Sciences, Volume 23, Issue 1, January 2023., 2023 Abstract Biotechnological production processes are sustainable approaches for the production of biobased components such as amino acids for food and feed industry. Scale‐up from ideal lab‐scale bioreactors to large‐scale processes is often accompanied by loss in productivity.
Manh Dat Hoang +5 more
wiley +1 more source
Structural analysis of the 5′ domain of the HeLa 18S ribosomal RNA by chemical and enzymatic probing [PDF]
, 1990 Valsan Mandiyan, M. Boublík
openalex +1 more source