Advanced NanoBiomed Research, EarlyView.The present study employs small RNA sequencing to identify the types and content of microRNAs (miRNAs) in four widely utilized plant‐derived extracellular vesicles (pEVs). The functional annotation reveals that the pEV miRNAs are involved in regulating the progression of human cancer and viral infection, thereby demonstrating the crosskingdom ...
Fei Wang +7 more
wiley +1 more source
HIV-1 virus cycle replication: a review of RNA polymerase II transcription, alternative splicing and protein synthesis [PDF]
arXiv, 2019 HIV virus replication is a time-related process that includes several stages. Focusing on the core steps, RNA polymerase II transcripts in an early stage pre-mRNA containing regulator proteins (i.e nef,tat,rev,vif,vpr,vpu), which are completely spliced by the spliceosome complex (0.9kb and 1.8kb) and exported to the ribosome for protein synthesis ...
arxiv
Food Science &Nutrition, Volume 11, Issue 1, Page 350-363, January 2023., 2023 Traditional Iranian butter samples were collected from different parts of Iran and were screened for the presence of Lactic acid bacteria. The selected LAB were identified to species level by biphasic approach. The ability of selected LAB to lower the cholestrol both in vitro and in situ was then determined.
Mahbubeh Ostadzadeh +2 more
wiley +1 more source
Karyotype analysis and physical mapping of 18S-5.8S-25S and 5S ribosomal RNA loci in species of genus Lens Miller (Fabaceae) [PDF]
, 2002 H. S. Balyan, Andreas Houben, R. Ahne
openalex +1 more source
Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis
Hepatology, EarlyView., 2022 EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu +16 more
wiley +1 more source
Nucleotide structure of the Scytalidium hyalinum and Scytalidium dimidiatum 18S subunit ribosomal RNA gene: evidence for the insertion of a group IE intron in the rDNA gene of S. dimidiatum [PDF]
, 2002 M. Machouart
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TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
Hepatology, EarlyView., 2022 The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam +10 more
wiley +1 more source
RBD-1, a nucleolar RNA-binding protein, is essential for Caenorhabditis elegans early development through 18S ribosomal RNA processing [PDF]
, 2004 Eiko Saijou
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pH‐Directed Capture‐SELEX for Nanomolar Affinity Aptamers for Kanamycin Detection
Analysis &Sensing, EarlyView.Considering the four pKa values of kanamycin A being all close to 7, two parallel SELEX experiments were carried out at pH 6 and 8. The pH 6 selection yielded a kanamycin aptamer with nanomolar affinity, which was used for fluorescent biosensor development.
Yichen Zhao, Juewen Liu
wiley +1 more source
Destabilization of mutated human PUS3 protein causes intellectual disability
Human Mutation, Volume 43, Issue 12, Page 2063-2078, December 2022., 2022 The homodimer of pseudouridine synthase 3 converts uridines at position 39 in tRNAs to pseudouridine (ψ), which affects tRNA stability and regulates RNA–protein interactions. Several patient‐derived variants of PUS3 have been associated with neurodegenerative diseases.
Ting‐Yu Lin +17 more
wiley +1 more source