Results 191 to 200 of about 587,426 (318)

Purine Chemistry in the Early RNA World at the Origins of Life: From RNA and Nucleobases Lesions to Current Key Metabolic Routes

open access: yesChemBioChem, EarlyView.
In the nascent processes of the beginnings and evolution of life, nucleobases and especially purines, ribonucleos(t)ides and primitive RNAs have been continuously modified. A RNA‐peptide world and key metabolic pathways probably have emerged from the corresponding chemical modifications resulting from adenine deamination, purine alkylation and ...
Jean‐Luc Décout   +1 more
wiley   +1 more source

Discovery and in vitro Reconstitution of Closoxazole Biosynthesis from Pyxidicoccus fallax

open access: yesChemBioChem, Accepted Article.
Benzoxazoles are important structural components of both bioactive natural products and pharmaceutical active ingredients. We investigated a putative benzoxazole gene cluster originating from the myxobacterium Pyxidicoccus fallax. This gene cluster was found to confer the ability for production of closoxazoles, which were recently discovered in the ...
Lucia Lernoud   +4 more
wiley   +1 more source

Molecular identification of Sarcocystis cruzi isolated from Iranian buffaloes in Guilan province

open access: yesBulgarian Journal of Veterinary Medicine
Sarcocystis species are prevalent in Iran and have economic and public health consequences on ani-mals and humans. The present study aimed at molecular identification of Sarcocystis spp.
F. Dameshghi   +3 more
doaj   +1 more source

Contemporary Perspectives on Chronic Renal Disorders

open access: yesChronic Diseases and Translational Medicine, EarlyView.
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok   +5 more
wiley   +1 more source

Long Term Weight Cycling Affects Fecal Microbiota of Mice

open access: yesMolecular Nutrition &Food Research, Volume 66, Issue 23, December 2022., 2022
Fighting obesity through dieting is not always sustained and results in a subsequent weight gain, a phenomenon referred to as weight cycling. We determined whether weight cycling affects mouse fecal bacteria on a long‐term basis. Compared to continuous High Fat (HF) or Low Fat (LF) diets, cyclic diet specifically alters the composition and function of ...
Christèle Humblot   +9 more
wiley   +1 more source

Molecular Typing of Sand Fly Species (Diptera, Psychodidae, Phlebotominae) from Areas Endemic for Leishmaniasis in Ecuador by PCR-RFLP of 18S Ribosomal RNA Gene

open access: hybrid, 2008
Yoshimi TERAYAMA   +6 more
openalex   +2 more sources

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