Results 201 to 210 of about 587,426 (318)

The longest 18S ribosomal RNA ever known [PDF]

open access: bronze, 1991
O‐Yu KWON   +2 more
openalex   +1 more source

Nanosecond Hyperquenching for Electron Cryo‐Microscopy Without Air‐Water Interface Artifacts

open access: yesChemistry – A European Journal, EarlyView.
A novel method for the ultrafast vitrification of the biological assemblies is assayed by the electron cryotomography. Protein specimens prepared by this method inherently lack the spatial/structural artifacts, which derive from the surface tension at the air‐water interface (AWI).
Utz H. Ermel   +2 more
wiley   +1 more source

A Fluorescent Aptasensor for Sensitive and Selective Determination of Epigenetic Cancer Biomarker N1‐Methyladenosine in Urine Samples

open access: yesChemistry – A European Journal, EarlyView.
Using N1‐methyladenosine, a cancer biomarker as a target, a highly selective DNA aptamer was obtained with excellent selectivity and affinity, allowing the detection with a limit of detection of 1.9 µm. Abstract N1‐methyladenosine (m1A) level in urine increases in the presence of cancer and is associated with the tumor size and stage.
Esra Bağda, Efkan Bağda, Juewen Liu
wiley   +1 more source

Total Synthesis of the Membrane Spanning Tetraether Lipid brGDGT Ia and Elucidation of Its Stereochemical Configuration

open access: yesChemistry – A European Journal, EarlyView.
Branched glycerol dialkyl glycerol tetraethers (brGDGT's) are membrane‐spanning lipids produced by Acidobacteria, and used extensively in geochemistry as proxies. The first total synthesis of brGDGT Ia has been achieved, elucidating the relative stereochemical configuration of the methyl branches in the chain as syn.
Samarpita Mahapatra   +5 more
wiley   +1 more source

Advances in Isotope Labeling for Solution Nucleic Acid NMR Spectroscopy

open access: yesChemPlusChem, Accepted Article.
The availability of nucleic acid structural biology methods still lags behind that of proteins, as evidenced by the significantly smaller number of structures deposited in the PDB. The highly skewed ratio of nucleic acid structures, relative to their protein counterparts (~1:50), is inverted with respect to the cellular output of RNA and proteins in ...
Stefan Hilber   +3 more
wiley   +1 more source

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