Results 251 to 260 of about 134,822 (364)

The normalization of gene expression data in melanoma: Investigating the use of glyceraldehyde 3-phosphate dehydrogenase and 18S ribosomal RNA as internal reference genes for quantitative real-time PCR [PDF]

, 2008
Orsi Giricz, Janelle L. Lauer‐Fields, Gregg B. Fields   +2 more
openalex   +1 more source

Poly(ethylene Glycol)‐Based Peptidomimetics (Pegtides) of Antimicrobial Peptides

ChemBioChem, EarlyView.
Polyethylene glycol (PEG) is commonly used to improve the pharmacokinetics and pharmacodynamics of therapeutic candidates by conjugation. Here PEG is exploited for peptidomimetic conversion of antimicrobial peptides (AMPs), as candidate antibacterial agents, by replacing their polyamide backbone. The pegtides obtained thereby can be readily synthesized
Conor Shine, John R. F. B. Connolly, Robert D. Murphy, Hazel Lafferty, Abdalmalek Alfnikh, Ned P. Buijs, Hawraa Shahrour, Nathaniel I. Martin, Eoghan O'Neill, George Amarandei, Jimmy Muldoon, Marc Maresca, Deirdre Fitzgerald‐Hughes, Marc Devocelle   +13 more
wiley   +1 more source

The 18S rRNA methyltransferase DIMT-1 regulates lifespan in the germline later in life. [PDF]

Nat Commun
Rothi MH, Sarkar GC, Haddad JA, Mitchell W, Ying K, Pohl N, Sotomayor-Mena RG, Natale J, Dellacona S, Gladyshev VN, Greer EL.   +10 more
europepmc   +1 more source

Diastereoselective, Diversifiable Synthesis and Biological Evaluation of the Virginiamycin Inducers, the Virginiae Butanolides

ChemBioChem, EarlyView.
Production of natural products is tightly regulated, resulting in many silent biosynthetic gene clusters. BarA is a repressor that downregulates production of the virginiamycin antibiotics. The VBs are ligands for BarA that reverse its repression of virginiamycin production.
Kylie G. Castator, Manuela Frias‐Gomez, Lauren E. Wilbanks, Elizabeth I. Parkinson   +3 more
wiley   +1 more source

Exploring the Substrate Flexibility of GrsB Thioesterase Leads to the Structural Reassignment of a Gramicidin S Variant

ChemBioChem, Accepted Article.
Gramicidin S (GS) is a cyclic decapeptide derived from two pentapeptides. The C‐terminal thioesterase (TE) domain of gramicidin S synthetase B (GrsB) dimerizes precursor pentapeptides and cyclizes the resulting linear decapeptide. Recently, a GS variant (GS‐SA), in which a single D‐Phe was replaced by L‐Ser(Allyl), was reported via precursor‐directed ...
Sho Konno, Tomoe Mizuguchi, Atsuko Suzuki, Miyu Tanaka, Fumihiro Ishikawa, Akihiro Taguchi, Atsuhiko Taniguchi, Genzoh Tanabe, Yoshio Hayashi   +8 more
wiley   +1 more source

Mapping and engineering RNA-driven architecture of the multiphase nucleolus. [PDF]

Nature
Quinodoz SA, Jiang L, Abu-Alfa AA, Comi TJ, Zhao H, Yu Q, Wiesner LW, Botello JF, Donlic A, Soehalim E, Bhat P, Zorbas C, Wacheul L, Košmrlj A, Lafontaine DLJ, Klinge S, Brangwynne CP.   +16 more
europepmc   +1 more source

Biochemical characteristics and applications of microalga Chlorella sorokiniana KNUA228 isolated from Ulleungdo

Environmental Progress &Sustainable Energy, EarlyView.
Abstract The increasing environmental and health challenges posed by fossil fuel dependency necessitate the exploration of renewable bioresources. Chlorella sorokiniana KNUA228, a microalga isolated from Ulleungdo, Republic of Korea, was investigated to evaluate its biotechnological potential. Molecular analyses confirmed its identity as C. sorokiniana,
Jin‐Won Lee, Jeong‐Mi Do, Ho‐Seong Suh, Yu‐Hee Seo, Su‐Bin Park, Ho‐Sung Yoon   +5 more
wiley   +1 more source

Protein Functional Effector (pfe) Noncoding RNAS Are Identical to Fragments from Various Noncoding RNAs. [PDF]

Int J Mol Sci
Patarca R, Haseltine WA.
europepmc   +1 more source

The 28S-18S rDNA intergenic spacer from Crithidia fasciculata: repeated sequences, length heterogeneity, putative processing sites and potential interactions between U3 small nucleolar RNA and the ribosomal RNA precursor

, 2000
Murray N. Schnare
openalex   +1 more source

Participation of Deoxyribonucleic Acid Polymerase a in Amplification of Ribosomal Deoxyribonucleic Acid in Xenopus laevis [PDF]

, 1981
Zimmermann, Wolfgang
core