Results 261 to 270 of about 134,822 (364)

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz   +9 more
wiley   +1 more source

Exploring the roles of snoRNA-induced ribosome heterogeneity in equine osteoarthritis. [PDF]

open access: yesFront Vet Sci
Chabronova A   +6 more
europepmc   +1 more source

Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines

open access: yesExploration, EarlyView.
This review provides a comprehensive analysis of recent advancements in extracellular vesicle (EV)‐based messenger RNA (mRNA) applications for therapeutics and vaccines. It systematically outlines strategies for mRNA encapsulation within EVs and elucidates the challenges associated with this technology, offering insights into future research directions
Qi Li   +6 more
wiley   +1 more source

Overreliance on Plasmodium 18S rRNA gene for malaria molecular diagnosis-inferences from systematic review. [PDF]

open access: yesMalar J
Deora N   +7 more
europepmc   +1 more source

Sputum Microbiota Compositions Correlate With Metabolome and Clinical Outcomes of COPD‐Bronchiectasis Association: A Prospective Cohort Study

open access: yesExploration, EarlyView.
This study aimed to determine how microbiota compositions (via 16S rRNA sequencing) correlate with clinical outcome and metabolome (via liquid chromatography/mass spectrometry) of CBA. Sputum microbiome and metabolome profiles of CBA were well separated from COPD but not bronchiectasis, partly driven by the higher abundance of Proteobacteria in CBA ...
Zhen‐feng He   +16 more
wiley   +1 more source

Microbiota‐Dependent Longevity Effects of Aronia Berry (Aronia melanocarpa) in Drosophila melanogaster

open access: yesFood Frontiers, EarlyView.
Aronia berry extract extends lifespan in Drosophila melanogaster by modulating commensal microbes, reducing oxidative stress, and activating the immune system via the Toll pathway. Its longevity effects are dependent on gut microbiota, highlighting the interplay between polyphenols, microbes, and aging.
Ji‐Hyeon Lee   +4 more
wiley   +1 more source

Mutations in GFAP Alter Early Lineage Commitment of Organoids

open access: yesGlia, EarlyView.
Mutations in GFAP alter lineage commitment of organoids. The severity of this commitment defect is dependent on the method of embryoid body formation. GFAP is expressed in iPSCs and during early stages of organoid development. Graphical abstract was created with BioRender.com .
Werner Dykstra   +14 more
wiley   +1 more source

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