Decoding Ribosome Stress: How NAT10 Influences Pancreatic Acinar Cell Survival and Cancer Development. [PDF]
Bailey-Lundberg JM.
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Transcriptional Regulation of Microglial Metabolic and Activation States by P2RY12
Transcriptionally, P2RY12‐deficient microglia show heightened metabolic activity, iron handling, and oxidative stress at baseline. Upon LPS challenge, impaired glutathione antioxidant responses suggest increased vulnerability to ferroptosis. ABSTRACT Microglia are the resident immune cells of the CNS.
Aida Oryza Lopez‐Ortiz+9 more
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First report of a Plasmodium malariae SSU rRNA gene variant in Africa associated with reduced amplification by nested PCR. [PDF]
Goto M+4 more
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The ribosomal RNA transcription landscapes of Plasmodium falciparum and related apicomplexan parasites. [PDF]
Mair G, Daiß JL, Engel C, Panov KI.
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What's New? Patients with stage II colon cancer exhibit considerable variation in prognosis. Consequently, decisions regarding the necessity of adjuvant chemotherapy in this population often rely on imperfect high‐risk criteria. Here, the authors developed a novel RNA‐based risk score, using NanoString nCounter technology, to stratify recurrence risk ...
Ulrik Korsgaard+8 more
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The Nucleolus: A Central Hub for Ribosome Biogenesis and Cellular Regulatory Signals. [PDF]
Ponti D.
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This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu+8 more
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Microbiota humanization drives human‐like metabolic and immune transcriptomic shifts in pigs
This study successfully established gut microbiota‐humanized pigs, achieved human‐like remodeling of the serum metabolome, and uncovered transcriptional alterations in immune cell subsets. These findings advance our understanding of how human gastrointestinal microorganisms affect host metabolism and the immune function in a porcine model.
Zhaoqi Zhang+9 more
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Extensive diversity of Symbiochlorum-related algae from environmental sequences and culture strains supports the description of the new family Symbiochloraceae (Ulvophyceae, Chlorophyta). [PDF]
Verbruggen H+5 more
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