Results 21 to 30 of about 81,162 (322)
The final step of 40S ribosomal subunit maturation is controlled by a dual key lock
eLife, 2021 Preventing premature interaction of pre-ribosomes with the translation apparatus is essential for translational accuracy. Hence, the final maturation step releasing functional 40S ribosomal subunits, namely processing of the 18S ribosomal RNA 3′ end, is ...
Laura Plassart +12 more
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BMC Molecular and Cell Biology, 2020 Background We have previously reported 18S and 25S ribosomal RNA molecules in Candida albicans resistant to processive 5′ → 3′ exonuclease, appearing as cells approached stationary growth phase. Initial analysis pointed to extra phosphate(s) at their 5′-
Jacob Fleischmann +4 more
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Transcriptional repressor NIR functions in the ribosome RNA processing of both 40S and 60S subunits. [PDF]
PLoS ONE, 2012 BACKGROUND: NIR was identified as an inhibitor of histone acetyltransferase and it represses transcriptional activation of p53. NIR is predominantly localized in the nucleolus and known as Noc2p, which is involved in the maturation of the 60S ribosomal ...
Jianguo Wu +7 more
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Structure of 18 S Ribosomal RNA in Native 40 S Ribosomal Subunits [PDF]
Journal of Biological Chemistry, 1997 We have analyzed the structure of 18 S rRNA in native 40 S subunits using chemical modification followed by primer extension. The native subunits were modified using the single-stranded specific reagents dimethyl sulfate and 1-cyclohexyl-3-(2-morpholinoethyl)carbodiimide metho-p-toluenesulfonate.
Y, Melander, L, Holmberg, O, Nygârd
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Arabidopsis RIBOSOMAL RNA PROCESSING7 Is Required for 18S rRNA Maturation [PDF]
The Plant Cell, 2018 Ribosome biogenesis is fundamental to growth and development in eukaryotes and is linked to human diseases and cancer. Arabidopsis thaliana MORPHOLOGY OF ARGONAUTE1-52 SUPPRESSED 2 (MAS2) participates in splicing and 45S ribosomal DNA (rDNA) expression.
Rosa Micol-Ponce +5 more
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Cells, 2021 Cockayne syndrome (CS) is a developmental disorder with symptoms that are typical for the aging body, including subcutaneous fat loss, alopecia, and cataracts.
Mingyue Qiang +5 more
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Stably expressed housekeeping genes across developmental stages in the two-spotted spider mite, Tetranychus urticae. [PDF]
PLoS ONE, 2015 Quantitative real-time PCR (qRT-PCR) is a reliable and reproducible technique for measuring mRNA expression. To facilitate gene expression studies and obtain more accurate qRT-PCR analysis, normalization relative to stable housekeeping genes is mandatory.
Chunxiao Yang +3 more
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The longest 18S ribosomal RNA ever known [PDF]
European Journal of Biochemistry, 1991 An EMBL4 recombinant phage which encodes one of the full length of the aphid ribosomal DNA has been isolated from the aphid genomic library. Determination of the complete nucleotide sequence of the aphid 18S rRNA gene revealed that it is 2469 bp with a G + C content of 59%.
O‐Yu KWON +2 more
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RNA Biology, 2022 snR30/U17 is a highly conserved H/ACA RNA that is required for maturation of the small ribosomal subunit in eukaryotes. By base-pairing to the expansion segment 6 (ES6) of 18S ribosomal RNA (rRNA), the snR30 H/ACA Ribonucleoprotein (RNP) indirectly ...
Timothy J. Vos, Ute Kothe
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Primary structure of rabbit 18S ribosomal RNA determined by direct RNA sequence analysis [PDF]
Nucleic Acids Research, 1984 The primary structure of rabbit 18S ribosomal RNA was determined by nucleotide sequence analysis of the RNA directly. The rabbit rRNA was specifically cleaved with T1 ribonuclease, as well as with E. coli RNase H using a Pst 1 DNA linker to generate a specific set of overlapping fragments spanning the entire length of the molecule.
J F, Connaughton +3 more
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