Results 71 to 80 of about 120,971 (346)

The Parasite that Causes Whirling Disease, \u3cem\u3eMyxobolus cerebralis\u3c/em\u3e, is Genetically Variable Within and Across Spatial Scales [PDF]

, 2012
Understanding the genetic structure of parasite populations on the natural landscape can reveal important aspects of disease ecology and epidemiology and can indicate parasite dispersal across the landscape.
Kerans, Billie L., Lodh, Nilanjan, Stevens, Lori   +2 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Partial methylation at Am100 in 18S rRNA of baker's yeast reveals ribosome heterogeneity on the level of eukaryotic rRNA modification.

PLoS ONE, 2014
Ribosome heterogeneity is of increasing biological significance and several examples have been described for multicellular and single cells organisms.
Markus Buchhaupt, Sunny Sharma, Stefanie Kellner, Stefanie Oswald, Melanie Paetzold, Christian Peifer, Peter Watzinger, Jens Schrader, Mark Helm, Karl-Dieter Entian   +9 more
doaj   +1 more source

Parasites and blood-meal hosts of the tsetse fly in Tanzania: a metagenomics study

Parasites & Vectors, 2022
Background Tsetse flies can transmit various Trypanosoma spp. that cause trypanosomiasis in humans, wild animals, and domestic animals. Amplicon deep sequencing of the 12S ribosomal RNA (rRNA) gene can be used to detect mammalian tsetse hosts, and the ...
Ju Yeong Kim, Jun Ho Choi, Sung-Hyun Nam, Robert Fyumagwa, Tai-Soon Yong   +4 more
doaj   +1 more source

Survey of vector-borne agents in feral cats and first report of Babesia gibsoni in cats on St Kitts, West Indies [PDF]

, 2017
Background: As there is little data on vector-borne diseases of cats in the Caribbean region and even around the world, we tested feral cats from St Kitts by PCR to detect infections with Babesia, Ehrlichia and spotted fever group Rickettsia (SFGR) and
Branford, Gillian Carmichael, Huang, Ke, Kelly, Patrick john, Köster, Liza, Li, Jing, Marchi, Silvia, Vandenplas, Michel, Wang, Chengming, Zhang, Jilei   +8 more
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Synergistic interaction network between the snR30 RNP, Utp23, and ribosomal RNA during ribosome synthesis

RNA Biology, 2022
snR30/U17 is a highly conserved H/ACA RNA that is required for maturation of the small ribosomal subunit in eukaryotes. By base-pairing to the expansion segment 6 (ES6) of 18S ribosomal RNA (rRNA), the snR30 H/ACA Ribonucleoprotein (RNP) indirectly ...
Timothy J. Vos, Ute Kothe
doaj   +1 more source

Maturation of the 90S pre-ribosome requires Mrd1 dependent U3 snoRNA and 35S pre-rRNA structural rearrangements [PDF]

, 2018
In eukaryotes, ribosome biogenesis requires folding and assembly of the precursor rRNA (pre-rRNA) with a large number of proteins and snoRNPs into huge RNA-protein complexes. In spite of intense genetic, biochemical and high-resolution cryo-EM studies in
Barandun, Beltrame, Beltrame, Ben-shem, Borovjagin, Borovjagin, Borovjagin, Burlacu, Chaker-Margot, Cheng, Coleman, Dragon, Dutca, Elena Burlacu, Fredrik Lackmann, Gavin, Grandi, Granneman, Granneman, Gulen, Hartshorne, Hartshorne, Hector, Henras, Hoang, Hughes, Hughes, Intine, Jin, Kornprobst, Koš, Krogan, Kudla, Lars Wieslander, Longtine, Low, Lundkvist, Lusvarghi, Létoquart, Marmier-Gourrier, Mortimer, Méreau, Osheim, Pestov, Pérez-Fernández, Sahasranaman, Sander Granneman, Sardana, Sardana, Sardana, Segerstolpe, Segerstolpe, Selega, Sergey Belikov, Shah, Sharma, Sharma, Smola, Sun, Tang, Tschochner, Velichutina, Wang, Wieslander, Woolford, Yeh   +65 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Genetic Diversity and Potential Function of Microbial Symbionts Associated with Newly Discovered Species of Osedax Polychaete Worms [PDF]

, 2007
We investigated the genetic diversity of symbiotic bacteria associated with two newly discovered species of Osedax from Monterey Canyon, CA, at 1,017-m (Osedax Monterey Bay sp. 3 "rosy" [Osedax sp. MB3]) and 381-m (Osedax Monterey Bay sp.
Goffredi, Shana K., Johnson, Shannon B., Vrijenhoek, Robert C.   +2 more
core   +2 more sources