Results 81 to 90 of about 309,135 (337)

From sea to land and beyond : new insights into the evolution of euthyneuran Gastropoda (Mollusca)

, 2008
Background The Euthyneura are considered to be the most successful and diverse group of Gastropoda. Phylogenetically, they are riven with controversy.
Annette Klussmann-Kolb, Kuhn, Kerstin, Albrecht, Christian, Klussmann-Kolb, Annette, Angela Dinapoli, Kerstin Kuhn, Streit, Bruno, Bruno Streit, Dinapoli, Angela, Christian Albrecht   +9 more
core   +1 more source

Meteora 18S rRNA gene phylogenetic trees

, 2022
Maximum Likelihood (ML) and Bayesian Inference (BI) phylogenetic trees of the 18S rRNA ...
Luis Javier Galindo (6432803)
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Multiple identification of most important waterborne protozoa in surface water used for irrigation purposes by 18S rRNA amplicon-based metagenomics.

International Journal of Hygiene and Environmental Health, 2018
Understanding waterborne protozoan parasites (WPPs) diversity has important implications in public health. In this study, we evaluated a NGS-based method as a detection approach to identify simultaneously most important WPPs using 18S rRNA high ...
Y. Moreno, L. Moreno-Mesonero, I. Amorós, R. Pérez, J. A. Morillo, J. Alonso   +5 more
semanticscholar   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Partial methylation at Am100 in 18S rRNA of baker's yeast reveals ribosome heterogeneity on the level of eukaryotic rRNA modification.

PLoS ONE, 2014
Ribosome heterogeneity is of increasing biological significance and several examples have been described for multicellular and single cells organisms.
Markus Buchhaupt, Sunny Sharma, Stefanie Kellner, Stefanie Oswald, Melanie Paetzold, Christian Peifer, Peter Watzinger, Jens Schrader, Mark Helm, Karl-Dieter Entian   +9 more
doaj   +1 more source

Parasites and blood-meal hosts of the tsetse fly in Tanzania: a metagenomics study

Parasites & Vectors, 2022
Background Tsetse flies can transmit various Trypanosoma spp. that cause trypanosomiasis in humans, wild animals, and domestic animals. Amplicon deep sequencing of the 12S ribosomal RNA (rRNA) gene can be used to detect mammalian tsetse hosts, and the ...
Ju Yeong Kim, Jun Ho Choi, Sung-Hyun Nam, Robert Fyumagwa, Tai-Soon Yong   +4 more
doaj   +1 more source

Beyond Blood Smears: Qualification of Plasmodium 18S rRNA as a Biomarker for Controlled Human Malaria Infections

American Journal of Tropical Medicine and Hygiene, 2019
. 18S rRNA is a biomarker that provides an alternative to thick blood smears in controlled human malaria infection (CHMI) trials. We reviewed data from CHMI trials at non-endemic sites that used blood smears and Plasmodium 18S rRNA/rDNA biomarker nucleic
A. Seilie, Ming Chang, Amelia E. Hanron, Zachary P. Billman, B. Stone, Kevin Zhou, T. Olsen, Glenda Daza, José Ortega, Kurtis R. Cruz, Nahum T Smith, S. Healy, S. Healy, S. Healy, Jillian Neal, C. Wallis, Lisa Shelton, Tracie Mankowski, S. Wong-Madden, Sebastian A Mikolajczak, A. Vaughan, S. Kappe, Matthew E. Fishbaugher, Will Betz, Mark F Kennedy, Jennifer C C Hume, A. Talley, S. Hoffman, S. Chakravarty, B. K. Sim, T. Richie, A. Wald, C. Plowe, K. Lyke, Matthew Adams, G. Fahle, E. Cowan, P. Duffy, J. Kublin, S. Murphy   +39 more
semanticscholar   +1 more source

The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site

, 2008
Ribosome biogenesis in eukaryotes requires the participation of a large number of ribosome assembly factors. The highly conserved eukaryotic nucleolar protein Nep1 has an essential but unknown function in 18S rRNA processing and ribosome biogenesis.
Wöhnert, Jens, Hart, P. John, Meyer, Britta, Entian, Karl-Dieter, Schirf, Virgil, Kötter, Peter, Taylor, Alexander B., Demeler, Borries, Leal, Belinda Z.   +8 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source