Results 101 to 110 of about 346,435 (241)
MDM2 prevents spontaneous tubular epithelial cell death and acute kidney injury [PDF]
, 2016 Murine double minute-2 (MDM2) is an E3-ubiquitin ligase and the main negative regulator of tumor suppressor gene p53. MDM2 has also a non-redundant function as a modulator of NF-kB signaling. As such it promotes proliferation and inflammation.
Anders, Hans-Joachim +10 more
core +2 more sources
Nucleic Acids Research, 1993 Intermolecular hybridization experiments show that murine 18S rRNA and 28S rRNA are capable of forming stable hybrid structures with mRNA from genes p53, c-myc and c-mos from the same species. Both 5'-uncoding and coding oncogene p53 mRNA regions contain fragments interacting with rRNA.
O V, Matveeva, S A, Shabalina
openaire +3 more sources
Characterization of the 18S rRNA Gene for Designing Universal Eukaryote Specific Primers
PLoS ONE, 2014 High throughput sequencing technology has great promise for biodiversity studies. However, an underlying assumption is that the primers used in these studies are universal for the prokaryotic or eukaryotic groups of interest.
Kenan Hadziavdic +5 more
semanticscholar +1 more source
Nucleic Acids Research, 2016 The chemically most complex modification in eukaryotic rRNA is the conserved hypermodified nucleotide N1-methyl-N3-aminocarboxypropyl-pseudouridine (m1acp3Ψ) located next to the P-site tRNA on the small subunit 18S rRNA.
B. Meyer +8 more
semanticscholar +1 more source
Genetic Diversity and Potential Function of Microbial Symbionts Associated with Newly Discovered Species of Osedax Polychaete Worms [PDF]
, 2007 We investigated the genetic diversity of symbiotic bacteria associated with two newly discovered species of Osedax from Monterey Canyon, CA, at 1,017-m (Osedax Monterey Bay sp. 3 "rosy" [Osedax sp. MB3]) and 381-m (Osedax Monterey Bay sp.
Goffredi, Shana K. +2 more
core +2 more sources
18S rRNA processing requires the RNA helicase-like protein Rrp3 [PDF]
Nucleic Acids Research, 1996 We report the identification of a new gene, RRP3 (rRNA processing), which is required for pre-rRNA processing. Rrp3 is a 60.9 kDa protein that is required for maturation of the 35S primary transcript of pre-rRNA and is required for cleavages leading to mature 18S RNA. RRP3 was identified in a PCR screen for DEAD box genes.
C L, O'Day +2 more
openaire +2 more sources
Scientific Reports, 2017 Anopheles mosquitoes are vectors of the human malaria parasite, Plasmodium falciparum. The vector microbiota is a likely factor influencing parasite transmission.
Eugeni Belda +7 more
doaj +1 more source
Ecological assessment of phytoplankton community via microscopic method and 18S rRNA gene sequencing in Pearl River Estuary [PDF]
E3S Web of Conferences, 2019 Monitoring phytoplankton community underpins our understanding of water quality and ecological functions. In this study, we approached phytoplankton abundance, community composition, and diversity by both microscopy and 18S rRNA gene sequencing ...
Peng Bo +5 more
doaj +1 more source
Compositional properties and thermal adaptation of 18S rRNA in vertebrates [PDF]
RNA, 2008 In order to investigate the influence of temperature on the GC level of the paired sequences of ribosomal 18S RNAs in vertebrates, we have studied their base composition in cold- and warm-blooded vertebrates using a stem-by-stem comparison. We observed that a number of stems of 18S ribosomal RNAs (rRNAs) are variable among species and that the majority
Annalisa, Varriale +2 more
openaire +2 more sources
BMC Plant Biology, 2010 Background Reference genes are commonly used as the endogenous normalisation measure for the relative quantification of target genes. The appropriate application of quantitative real-time PCR (RT-qPCR), however, requires the use of reference genes whose ...
Kundu Jiban K, Jarošová Jana
doaj +1 more source