Results 71 to 80 of about 309,135 (337)

The Bowen–Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Psi1191 in yeast 18S rRNA

, 2010
The Nep1 (Emg1) SPOUT-class methyltransferase is an essential ribosome assembly factor and the human Bowen–Conradi syndrome (BCS) is caused by a specific Nep1D86G mutation. We recently showed in vitro that Methanocaldococcus jannaschii Nep1 is a sequence-
Valeska Schilling, Jan Philip Wurm, Britta Meyer, Michael Karas, Kötter, Peter, Bahr, Ute, Schilling, Valeska, Buchhaupt, Markus, Wöhnert, Jens, Ute Bahr, Karl-Dieter Entian, Matthias S. Leisegang, Karas, Michael (Prof. Dr.), Martin Held, Heckel, Alexander, Leisegang, Matthias S., Peter Kötter, Markus T. Bohnsack, Entian, Karl-Dieter, Markus Buchhaupt, Bohnsack, Markus, Held, Martin, Alexander Heckel, Meyer, Britta, Leisegang, Matthias, Jens Wöhnert, Karas, Michael, Wurm, Jan Philip   +27 more
core   +1 more source

Yeast Rrp8p, a novel methyltransferase responsible for m1A 645 base modification of 25S rRNA

, 2012
Ribosomal RNA undergoes various modifications to optimize ribosomal structure and expand the topological potential of RNA. The most common nucleotide modifications in ribosomal RNA (rRNA) are pseudouridylations and 2'-O methylations (Nm), performed by H ...
Sharma, Sunny, Watzinger, Peter, Lamberth, Stefanie, Entian, Karl-Dieter, Kötter, Peter, Peifer, Christian   +5 more
core   +1 more source

Restriction enzyme digestion of host DNA enhances universal detection of parasitic pathogens in blood via targeted amplicon deep sequencing

Microbiome, 2018
Background Targeted amplicon deep sequencing (TADS) of the 16S rRNA gene is commonly used to explore and characterize bacterial microbiomes. Meanwhile, attempts to apply TADS to the detection and characterization of entire parasitic communities have been
Briana R. Flaherty, Eldin Talundzic, Joel Barratt, Kristine J. Kines, Christian Olsen, Meredith Lane, Mili Sheth, Richard S. Bradbury   +7 more
doaj   +1 more source

Application of dried blood spot sample pooling strategies for Plasmodium 18S rRNA biomarker testing to facilitate identification of infected persons in large-scale epidemiological studies

Malaria Journal, 2021
Background Plasmodium 18S rRNA is a sensitive biomarker for detecting Plasmodium infection in human blood. Dried blood spots (DBS) are a practical sample type for malaria field studies to collect, store, and transport large quantities of blood samples ...
Ming Chang, Selena Johnston, Annette M. Seilie, Dianna Hergott, Sean C. Murphy   +4 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Characterization of the two intra-individual sequence variants in the 18S rRNA gene in the plant parasitic nematode, Rotylenchulus reniformis. [PDF]

PLoS ONE, 2013
The 18S rRNA gene is fundamental to cellular and organismal protein synthesis and because of its stable persistence through generations it is also used in phylogenetic analysis among taxa.
Seloame T Nyaku, Venkateswara R Sripathi, Ramesh V Kantety, Yong Q Gu, Kathy Lawrence, Govind C Sharma   +5 more
doaj   +1 more source

Analysis of rRNA processing and translation in mammalian cells using a synthetic 18S rRNA expression system [PDF]

Nucleic Acids Research, 2012
Analysis of processing, assembly, and function of higher eukaryotic ribosomal RNA (rRNA) has been hindered by the lack of an expression system that enables rRNA to be modified and then examined functionally. Given the potential usefulness of such a system, we have developed one for mammalian 18S rRNA. We inserted a sequence tag into expansion segment 3
Burman, Luke G., Mauro, Vincent P.
openaire   +2 more sources

Seasonality of Planktonic Freshwater Ciliates: Are Analyses Based on V9 Regions of the 18S rRNA Gene Correlated With Morphospecies Counts?

Frontiers in Microbiology, 2019
Ciliates represent central nodes in freshwater planktonic food webs, and many species show pronounced seasonality, with short-lived maxima of a few dominant taxa while many being rare or ephemeral.
Gianna Pitsch, Estelle P. Bruni, Dominik Forster, Zhishuai Qu, B. Sonntag, T. Stoeck, T. Posch   +6 more
semanticscholar   +1 more source

Quantitative analysis of snoRNA association with pre-ribosomes and release of snR30 by Rok1 helicase [PDF]

, 2008
In yeast, three small nucleolar RNAs (snoRNAs) are essential for the processing of pre-ribosomal RNA—U3, U14 and snR30—whereas 72 non-essential snoRNAs direct site-specific modification of pre-rRNA. We applied a quantitative screen for alterations in the
Martin Kos, Markus T Bohnsack, Bohnsack, Markus T., Tollervey, David, David Tollervey, Kos, Martin, Bohnsack, Markus   +6 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source