Results 11 to 20 of about 357 (143)

A review of the analytical techniques for the detection of anabolic–androgenic steroids within biological matrices [PDF]

WIREs Forensic Science, Volume 6, Issue 1, January/February 2024., 2023
Anabolic–androgenic steroids (AASs) and other image and performance enhancing drugs (IPEDs) are controlled by governments and sport institutions such as the World Anti-doping Agency (WADA).
De Paoli, Giorgia, Hall, Sarah, Harries, Richard L., Nisbet, Lorna A.   +3 more
core   +4 more sources

Same, but different: Variations in fragment ions among stereoisomers of a 17α-methyl steroid in gas chromatography/electron ionization mass spectrometry. [PDF]

Rapid Commun Mass Spectrom
Rationale Gas chromatography/electron ionization mass spectrometry (GC/EI-MS) is a well-established tool for the identification of unknown compounds such as new metabolites of xenobiotics.
Steff J, Parr MK.
europepmc   +4 more sources

Analysis of doping control samples using supercritical fluid chromatography-tandem mass spectrometry: Ready for routine use [PDF]

Journal of Separation Science, Volume 46, Issue 7, April 2023., 2023
Supercritical fluid chromatography is proving to be a good separation and sample preparation tool for various analytical applications and, as such, has gained the attention of the anti-doping community.
Botrè, Francesco, Cowan, David, de la Torre, Xavier, Gavrilović, Ivana, Parr, Maria Kristina, Wuest, Bernhard   +5 more
core   +2 more sources

Routine application of SFC-MS in doping control: Analysis of 3 × 1000 urine samples using three different SFC-MS instruments [PDF]

Drug Testing and Analysis, Volume 16, Issue 7, Page 726-736, July 2024.
Supercritical fluid chromatography-mass spectrometry (SFC-MS) has proved to be a beneficial tool for sample analysis for a wide variety of compounds and, as such, has recently gained the attention of the anti-doping community.
Botrè, Francesco, Braidman, Emmanuelle, Cowan, David, Danaceau, Jonathan, de la Torre, Xavier, Gavrilović, Ivana, Parr, Maria Kristina, Wüst, Bernhard   +7 more
core   +2 more sources

Avoid Falsely Accusing Female Athletes Who Use Levonorgestrel of Doping. [PDF]

Drug Test Anal
Levonorgestrel, a hormonal contraceptive, metabolises to 18‐methyl‐19‐noretiocholanolone which is also the main metabolite of the prohibited substance 18‐methyl‐19‐nortestosterone. Analysing for levonorgestrel and/or tetrahydronorgestrel is essential to avoid misinterpreting 18‐methyl‐19‐noretiocholanolone findings.
Andersson A, Pohanka A, Lehtihet M, Ekström L.   +3 more
europepmc   +2 more sources

Detection of doping substances in paired dried blood spots and urine samples collected during doping controls in Danish fitness centers. [PDF]

Drug Test Anal
We developed a feasible, sensitive, and robust method for simultaneous detection of 19 selected prohibited substances from S1 to S5 in dried blood spots (DBS) and compared the detectability of these prohibited substances in paired DBS and urine samples collected during doping controls in Danish fitness centers. Abstract The use of dried blood spot (DBS)
Levernæs MCS, Solheim SA, Broderstad L, Zandy E, Mørkeberg J, Dehnes Y.   +5 more
europepmc   +2 more sources

Simultaneous quantitation and identification of intact Nandrolone phase II oxo-metabolites based on derivatization and inject LC-MS/(HRMS) methodology. [PDF]

Drug Test Anal
Accurate and convenient analysis of the intact phase II oxo‐metabolites of nandrolone under the provisions of WADA's TD2023IDCR was accomplished with a dilute derivatization reagent (Girard's reagent T) and inject strategy. Abstract Α sensitive and selective derivatization and inject method for the quantification of intact nandrolone phase II oxo ...
Sakellariou P, Kiousi P, Petrou M, Angelis YS.   +3 more
europepmc   +2 more sources

Dietary Supplements as Source of Unintentional Doping. [PDF]

Biomed Res Int, 2022
Background. The substances used in sport could be divided into two major groups: those banned by the World Anti‐Doping Agency and those which are not. The prohibited list is extremely detailed and includes a wide variety of both medicinal and nonmedicinal substances. Professional athletes are exposed to intense physical overload every day.
Kozhuharov VR, Ivanov K, Ivanova S.
europepmc   +2 more sources

Effects of Dietary Protein Level on the Microbial Composition and Metabolomic Profile in Postweaning Piglets. [PDF]

Oxid Med Cell Longev, 2022
Since the human and porcine digestive systems have similar anatomical structures and physiological functions, pigs are a useful animal model for studying human digestive diseases. By investigating intestinal metabolites in piglets after weaning, this study attempted to identify the inherent connection between dietary protein levels and changes in the ...
Gao J, Liu Z, Wang C, Ma L, Chen Y, Li T.   +5 more
europepmc   +2 more sources

Effects of the administration of miconazole by different routes on the biomarkers of the "steroidal module" of the Athlete Biological Passport. [PDF]

Drug Test Anal, 2021
The results obtained from the investigation of the influence of miconazole administration on the parameters included in the “steroidal module” of the Athlete Biological Passport were presented. After oral and buccal administration of miconazole, the levels of the markers of the steroid profile were significantly altered, whereas no effects were ...
Mazzarino M, Comunità F, de la Torre X, Molaioni F, Botrè F.   +4 more
europepmc   +2 more sources