Results 1 to 10 of about 1,483 (54)
What anabolic–androgenic steroids reveal about the limits of current harm reduction models
Abstract Background Harm reduction has largely been shaped by responses to psychoactive drug use where the most urgent harms are acute. These models focus on overdose, blood‐borne viruses, and rapid‐onset toxicity related harms. When applied wholesale to anabolic–androgenic steroids (AAS), they obscure the distinctive pharmacology, consumer typologies,
Timothy Piatkowski +2 more
wiley +1 more source
Current Approaches to Support Patients to Withdraw From Image and Performance Enhancing Drugs
ABSTRACT Image and performance‐enhancing drugs (IPEDs) include agents such as androgens, growth hormone, and erythropoietin, which are used to enhance appearance and physical performance. Androgens, also known as anabolic‐androgenic steroids (AAS), are the most used IPEDs worldwide.
Elizabeth Hyams +3 more
wiley +1 more source
Molecular mechanism diagram of Gly‐A in the treatment of acute and chronic exercise‐fatigue. ABSTRACT Background Glycyrrhizic acid (Gly‐A) exhibits anti‐inflammatory and antioxidant effects in various central nervous system disorders. Acute fatigue and chronic fatigue (CF) are associated with serious physical and psychological effects.
Xin‐ying Cai +9 more
wiley +1 more source
Anabolic‐androgenic steroid use is associated with cardiac structural remodeling and functional impairment in strength‐trained athletes. Longer exposure was significantly associated with greater reductions in LVEF and increases in LVMI and posterior wall thickness, while other echocardiographic abnormalities showed heterogeneous temporal patterns ...
Matheus de Medeiros Fernandes +13 more
wiley +1 more source
Dried blood spot (DBS) analysis enables minimally invasive blood collection with strong analyte stability and simplified logistics, supporting anti‐doping applications beyond traditional matrices. Recent advances address hematocrit, volume variability, and matrix effects while expanding coverage to steroid esters, World Anti‐Doping Agency‐listed ...
Jihyun Yoon +4 more
wiley +1 more source
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley +1 more source
ABSTRACT Background Despite ongoing interest in anabolic therapies for sarcopenia and cachexia, pharmacological interventions are being developed to counteract age‐ and condition‐related losses of muscle mass and strength. This systematic review and meta‐analysis evaluated the effect of nandrolone decanoate on lean soft tissue (LST), fat mass, handgrip
Konstantinos Prokopidis +13 more
wiley +1 more source
Direct Ambient Mass Spectrometry for Food, Beverage, and Agricultural Sample Analysis and Research
ABSTRACT Ambient and direct mass spectrometry (MS) methods are becoming increasingly used for the rapid analysis of food, beverage and agricultural samples. Novel ionization approaches combined with targeted, or untargeted workflows provide analytical outcomes within a greatly reduced time period compared to traditional separation science coupled with ...
Leigh M. Schmidtke +3 more
wiley +1 more source
Preventing Atherosclerotic Cardiovascular Disease in Young Male Androgen Abusers
Androgen abuse is an underrecognized ASCVD risk enhancer in young men. Improved risk assessment—integrating androgen exposure, imaging, and individualized prevention—may help in the management of long‐term cardiovascular risk in this population. ABSTRACT Background Androgen abuse among young men is a prevalent yet under recognized risk factor for ...
Peter Bond +3 more
wiley +1 more source
Purtscher‐like retinopathy is a rare microvascular retinal disorder characterized by sudden visual loss and distinctive fundoscopic findings, often associated with systemic vascular insults. We report a 31‐year‐old male presenting with bilateral sudden blurred vision, hypertensive crisis, and renal failure following excessive intake of anabolic ...
Sahel Khazaei +2 more
wiley +1 more source

