Results 21 to 30 of about 1,483 (54)

Detection of Anabolic Androgenic Steroids and Steroid Esters—Comparing Dried Blood Spots Collection Devices and Urine Samples

Drug Testing and Analysis, Volume 17, Issue 12, Page 2374-2383, December 2025.
DBS (Capitainer‐B50 and Tasso‐M20) enabled detection of testosterone esters in all participants, whereas urine testing (T/E) missed cases including potential UGT2B17 del/del carriers and individuals with testosterone prescription. More AAS and steroid‐esters could be detected in Capitainer‐B50 versus Tasso‐M20.
Tina Suominen, Jeanette von Walden, Laura Harju, Anton Pohanka, Jenny Schulze, Mikael Lehtihet, Lena Ekström   +6 more
wiley   +1 more source

Prevalence of AAS‐Positive Samples at Drug Abuse Laboratory Sweden Between 2014 and 2023 and Sub‐Study of Dual Use of AAS and Narcotics

Drug Testing and Analysis, Volume 17, Issue 12, Page 2421-2428, December 2025.
Throughout 2014–2023, over 20,000 AAS analyses have been conducted at the drug of abuse laboratory, Karolinska University Hospital. Approximately 20% and 2% of the samples have been positive for AAS, with no trends of increase or decrease. Around 50% of the AAS‐positive samples were also positive for narcotics (year 2022–2023), with gender differences;
Kim Petterson Bohlin, Tomas Villén, Oscar Hopcraft, Anton Pohanka, Lena Ekström   +4 more
wiley   +1 more source

Combating muscle atrophy: emerging therapeutic targets that are fiber‐type‐specific

The FEBS Journal, Volume 292, Issue 24, Page 6481-6496, December 2025.
Inflammation, denervation or decreased insulin signaling activate proteolysis and cause muscle wasting. Pathological conditions like obesity and DMD can also exacerbate atrophy via PGD2–RhoA–ROCK2 signaling. In contrast, exercise, dietary interventions, and pharmacological agents can activate Ca2+/calcineurin–NFAT and AMPK–PGC‐1α–MEF pathways ...
Samrat Chakraborty, Raz Ben‐David, Shenhav Shemer   +2 more
wiley   +1 more source

Simplified Analysis of Native Steroid Esters in Dried Blood Spots by LC–MS3

Journal of Mass Spectrometry, Volume 60, Issue 11, November 2025.
ABSTRACT Steroidal esters (e.g., testosterone, nandrolone and boldenone esters) belong to the substance class prohibited in professional sport that is particularly frequently abused due to its considerable performance‐enhancing effects. Thus, a high number of adverse analytical findings in doping controls is reported every year.
Andreas Thomas, Jasmin Thelen, Panagiotis Sakellariou, Mario Thevis   +3 more
wiley   +1 more source

Use of high-dose nandrolone aggravates septic shock in a mouse model [PDF]

, 2011
Nandrolone, an anabolic-androgenic steroid, is widely misused by athletes who wish to rapidly increase muscle mass and performance. An increasing number of reports have indicated that nandrolone may affect and modulate the immune system. This study aimed
Lin, Che, 林喆, 郭守仁,, Che Lin, 陳守棟,, Dar-Ren Chen, 陳守棟, Shou-Tung Chen, 簡素玉, 郭守仁, Su-Yu Chien, Chen, Dar-Ren, 林喆,, 簡素玉,, 陳達人,, Chien, Su-Yu, Chen, Shou-Tung, Kuo, Shou-Jen, Shou-Jen Kuo, 陳達人   +19 more
core   +1 more source

Survey on 9 years of anti‐doping controls in horse races in Italy

Equine Veterinary Journal, Volume 57, Issue 6, Page 1592-1599, November 2025.
Abstract Background Doping in racehorses is a threat to horse welfare and the integrity of the sport. Despite its relevance, the literature on the prevalence of anti‐doping violations worldwide is limited. Objectives To analyse anti‐doping violations in racehorses in Italy. Study Design Retrospective observational study.
Mariana Roccaro, Riccardo Rinnovati, Luca Stucchi, Federica La Rocca, Giuseppe Cascio, Angelo Peli   +5 more
wiley   +1 more source

Heart Reaction to Nandrolone Decanoate plus Two Different Intensities of Endurance Exercise: Electrocardiography and Stereological Approach [PDF]

, 2018
Background: Regarding the negative effects of androgenic anabolic steroids (AASs) abuse, the long-term effect of nandrolone decanoate with/without two intensities of endurance exercise training was investigated on heart tissue and electrocardiogram (ECG)
Vida Naderi-Boldaji, Forouzan Rafie, Mahdieh Yoosefnia, Siyavash Joukar, Hamidreza Nasri   +4 more
core   +2 more sources

Lead Astray? The Hidden Contaminants in Australian Anabolic–Androgenic Steroid Market and Their Potential Health Impact

Drug and Alcohol Review, Volume 44, Issue 6, Page 1641-1647, September 2025.
ABSTRACT Introduction Unregulated anabolic–androgenic steroid (AAS) markets are a global phenomenon with significant variability in product composition and purity. This study aimed to determine the chemical composition of AAS sold in Australia. Methods This study analysed anonymously donated AAS samples.
Alison Craven, Jason Ferris, Suzanne Nielsen, Timothy Piatkowski   +3 more
wiley   +1 more source

Nandrolone and bone regeneration

, 2006
Aim of this study is to achieve better bone quality using steroids since many attempts to find factors useful in boosting bone regeneration has failed. In a preliminary study performed in a mini-pig model we analyzed the effect of stanazolol.
DI NUCCI, AMALIA, BRUSOTTI, CESARE, Davide Zaffe, Alessandro Addis, RIZZO, SILVANA, RODRIGUEZ Y BAENA, RUGGERO   +5 more
core  

Nandrolone potentiates arrhythmogenic effects of cardiac ischemia in the rat

, 2007
© The Author 2007. Published by Oxford University Press on behalf of the Society of Toxicology. All rights reserved.Anabolic steroid abuse has been associated with thrombosis and arteriosclerosis, both of which predispose to myocardial ischemia and ...
Abeywardena, M., Adams, M., Kennedy, J., Mahinda Y. Abeywardena, Michael J. Adams, Benjamin D. Phillis, Jennifer A. Kennedy, Rodney J. Irvine, Phillis, B., Irvine, R.   +9 more
core   +1 more source